All of the evidence provided on Hippocampome.org are quotes from scientific texts.
However, because quoted passages may be difficult to understand in isolation, contextual information and expanded abbreviations set in square brackets have been added for clarity.
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EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p433, Table 1
"Table 1 Number of mGlu1a-, CB1- and calbindin-immunolabeled neurons in CA1 stratum radiatum and relative percentage of coexistence"
Interpretation notes: Glutamatergic and GABAergic mGluR1a- types in CA1 SR are probably CB1- by contrapositive logic; Clopper-Pearson confidence interval lower bound = 84.3% (n = 81/88)
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p1220, right top
"In our attempts to identify the CCK[cholecystokinin]-negative subpopulation we found no colocalization of CB1 [cannabinoid type 1] receptor and parvalbumin, as shown previously (Tsou et al., 1999; Katona et al., 1999b, 2000, 2001)."
Interpretation notes: Glutamatergic and GABAergic PV+ types in CA1 SLM_SR_SP_SO are probably CB1-
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p1217, Table 1
"Table 1. Colocalization of type 1 cannabinoid receptor (CB1) and cholecystokinin (CCK) in the hippocampus and dentate gyrus at different post-natal ages."
Interpretation notes: Glutamatergic and GABAergic CCK- types in CA1 & CA3 SLM_SR_SP_SO are probably CB1- by contrapositive logic; Clopper-Pearson confidence interval lower bound = 90.2% (n = 510/550)
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p1217, Fig. 3
"Fig. 3. Occurrence of cholecystokinin (CCK)/type 1 cannabinoid receptor (CB1) double-labelled cells in proportion of all CB1-immunoreactive (ir) neurons in the CA1 and CA3 subfields as well as in the supra- and infrapyramidal blade of the dentate gyrus (DG) at different post-natal ages. Data from the infrapyramidal blade on the fourth post-natal day were not taken into consideration as the blade was highly immature, not yet formed completely and immunoreactivity for CCK was weak. Data represent means after analysis of six sections from three animals at each age +/- SD."
Interpretation notes: Glutamatergic and GABAergic CCK- types in CA1 SLM_SR_SP_SO are probably CB1- by contrapositive logic
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p1220, right top
"In our attempts to identify the CCK[cholecystokinin]-negative subpopulation we found no colocalization of CB1 [cannabinoid type 1] receptor and parvalbumin, as shown previously (Tsou et al., 1999; Katona et al., 1999b, 2000, 2001)."
Interpretation notes: Glutamatergic and GABAergic PV+ types in CA1 SLM_SR_SP_SO are probably CB1- by contrapositive logic
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p971, left bot
"The cell bodies immunopositive for each marker are distinct (Fig. 3C), indicating that CB1 [cannabinoid] receptors are not expressed on parvalbumin-containing interneurons."
Interpretation notes: Glutamatergic and GABAergic PV+ types in CA1 SLM_SR_SP_SO are probably CB1-
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p971, left bot
"The cell bodies immunopositive for each marker are distinct (Fig. 3C), indicating that CB1 [cannabinoid] receptors are not expressed on parvalbumin-containing interneurons."
Interpretation notes: Glutamatergic and GABAergic PV+ types in CA1 SLM_SR_SP_SO are probably CB1- by contrapositive logic
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negative; confirmed by inference(s)
