negative inference; confirmed by additional inferences
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EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p562, left mid
"The lack of PV [parvalbumin] immunoreactivity in VGLUT3[vesicular glutamate transporter type 3]-positive somata and boutons, the obligatory coexpression of VGLUT3 and CCK [cholecystokinin] in interneuronal somata and the perisomatic location of boutons double-labelled for GAD and VGLUT3 in the principal cell layers demonstrate that VGLUT3 is present in a distinct type of basket cell. Some basket cells expressing CCK but negative for PV also express VIP [vasoactive intestinal polypeptide] (reviewed in Freund & Buzsaki, 1996). However, in our material, neither VIP-positive cell bodies nor boutons were positive for VGLUT3. Therefore, the CCK- and VGLUT3-positive cells constitute a novel subtype of basket cell {CA1 Basket CCK+}."
Interpretation notes: Glutamatergic and GABAergic CCK- types in CA1 SLM_SR_SP_SO are probably vGlut3- by contrapositive logic
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p 557 right top
"Somata double-labelled for VGLUT3 [vesicular glutamate transporter type 3] and CCK [cholecystokinin] were typically negative for CB [calbindin] (Fig. 4C and Table 2)."
Interpretation notes: Glutamatergic and GABAergic CB+ types in CA1 SLM_SR_SP_SO are probably vGlut3- by contrapositive logic; Clopper-Pearson confidence interval lower bound = 95.3% (n = 181/184)
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p 557, Table 2
"Table 2. Suppopulations of CCK interneurons, which were colabelled for VGLUT3, CB, CR, or VIP"
Interpretation notes: Glutamatergic and GABAergic CB+ types in CA1 SLM_SR_SP_SO are probably vGlut3- by contrapositive logic; Clopper-Pearson confidence interval lower bound = 95.3% (n = 181/184)
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negative inference; confirmed by additional inferences