negative inference; confirmed by additional inferences
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EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p 312, left top
Linking PMID: 8783251 Linking Quote: All necessary morphological evidence is present in this self-same publication.
"CCK [cholecystokinin] was co-localized with VIP [vasoactive intestinal polypeptide] in basket cells, but was absent from the other types (except for a few cells with the axon in stratum radiatum and dendrites in all layers.) Calbindin and parvalbumin showed no coexistence with VIP. Co-localization with GABA, revealed 100% coexistence with VIP."
Interpretation notes: Glutamatergic and GABAergic CB+ types in CA1 SLM_SR_SP_SO are probably VIP- by contrapositive logic
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p 311, right middle
"From 210 VIP-immunoreactive interneurons in CA1, 208 were negative for calbindin D-28k (Fig. 8C, D) whereas none of the 44 VIP-containing neurons in CA3 showed calbindin D-28k immunofluorescence."
Interpretation notes: Glutamatergic and GABAergic CB+ types in CA1 SLM_SR_SP_SO are probably VIP- by contrapositive logic; Clopper-Pearson confidence interval lower bound = 96.6% (n = 208/210)
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p841, Table 1
"TABLE 1. Proportion of a1 subunit-immunoreactive neurons containing GABA,
calcium-binding proteins and neuropeptide "
Interpretation notes: Glutamatergic and GABAergic GABAa alpha1+ types in CA1 SLM_SR_SP_SO are probably VIP-
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p841, Table 2
"TABLE 2. Proportion of neurons stained for GABA, calcium-binding proteins
and neuropeptides expressing the a1 subunit-immunoreactivity "
Interpretation notes: Glutamatergic and GABAergic GABAa alpha1+ types in CA1 SLM_SR_SP_SO are probably VIP- by contrapositive logic
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negative inference; confirmed by additional inferences
