positive * Contradictory evidence exists (open all evidence to view)
All of the evidence provided on Hippocampome.org are quotes from scientific texts.
However, because quoted passages may be difficult to understand in isolation, contextual information and expanded abbreviations set in square brackets have been added for clarity.
"In our attempts to identify the CCK[cholecystokinin]-negative subpopulation we found no colocalization of CB1 [cannabinoid type 1] receptor and parvalbumin, as shown previously (Tsou et al., 1999; Katona et al., 1999b, 2000, 2001)."
Interpretation notes: Glutamatergic and GABAergic PV+ types in CA1 SLM_SR_SP_SO are probably CB1-
"In our attempts to identify the CCK[cholecystokinin]-negative subpopulation we found no colocalization of CB1 [cannabinoid type 1] receptor and parvalbumin, as shown previously (Tsou et al., 1999; Katona et al., 1999b, 2000, 2001)."
Interpretation notes: Glutamatergic and GABAergic PV+ types in CA1 SLM_SR_SP_SO are probably CB1- by contrapositive logic
"The cell bodies immunopositive for each marker are distinct (Fig. 3C), indicating that CB1 [cannabinoid] receptors are not expressed on parvalbumin-containing interneurons."
Interpretation notes: Glutamatergic and GABAergic PV+ types in CA1 SLM_SR_SP_SO are probably CB1-
"The cell bodies immunopositive for each marker are distinct (Fig. 3C), indicating that CB1 [cannabinoid] receptors are not expressed on parvalbumin-containing interneurons."
Interpretation notes: Glutamatergic and GABAergic PV+ types in CA1 SLM_SR_SP_SO are probably CB1- by contrapositive logic
"Co-localization studies using the 'mirror' technique showed that in
the rat the overwhelming majority of the Enk cells were CR-IR (19
out of 21) (Fig. 3A,B) and VIP-IR (23 out of 24, Fig. 3C,D). This
was in agreement with the conclusion drawn from morphology and
laminar distribution of the Enk-IR cells, which were similar to the
features of VIP- and CR-positive neurons."
Interpretation notes: Glutamatergic and GABAergic CR- types in CA1 SLM_SR_SP_SO are probably Enk- by contrapositive logic; Clopper-Pearson confidence interval lower bound = 69.6% (n = 19/21)
"Co-localization studies using the 'mirror' technique showed that in
the rat the overwhelming majority of the Enk cells were CR-IR (19
out of 21) (Fig. 3A,B) and VIP-IR (23 out of 24, Fig. 3C,D). This
was in agreement with the conclusion drawn from morphology and
laminar distribution of the Enk-IR cells, which were similar to the
features of VIP- and CR-positive neurons."
Interpretation notes: Glutamatergic and GABAergic VIP- types in CA1 SLM_SR_SP_SO are probably Enk- by contrapositive logic; Clopper-Pearson confidence interval lower bound = 78.9% (n = 23/24)
"In these experiments, all the cells of the hippocampus immunoreactive for somatostatin were strongly immunoreactive for mGluR[metabotropic glutamate receptor]lalpha, and likewise the cells immunoreactive for mGluRla were also immunoreactive for somatostatin (Figures 2A and 2B)."
Interpretation notes: Glutamatergic and GABAergic mGluR1a- types in CA1 SLM_SR_SP_SO are probably SOM- by contrapositive logic
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