All of the evidence provided on Hippocampome.org are quotes from scientific texts.
However, because quoted passages may be difficult to understand in isolation, contextual information and expanded abbreviations set in square brackets have been added for clarity.
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EXPRESSION: positive
ANIMAL: rat
PROTOCOL: mRNA
Page location: p470, left bottom
Linking PMID: 17503488 Linking Quote: Principal neurons identified by the presence of their somata in the principal cell layer, which is densely packed with and nearly homogeneous for the somata of the subregion's principal neurons (Czeh et al., 2013, Acta Biologica Hungarica).
"In control animals (n = 8/8), all principal cells of the
hippocampal formation were labeled for VGLUT1 mRNA,
including the pyramidal cells of the CA1, CA2, and CA3
regions of the hippocampus and the granule cells of the
dentate gyrus (Fig. 1A) as previously reported for rodents
(Fremeau et al., 2001; Miyazaki et al., 2003). "
EXPRESSION: positive
ANIMAL: rat
PROTOCOL: mRNA
Page location: p471, Fig. 1
Linking PMID: 17503488 Linking Quote: Principal neurons identified by the presence of their somata in the principal cell layer, which is densely packed with and nearly homogeneous for the somata of the subregion's principal neurons (Czeh et al., 2013, Acta Biologica Hungarica).
"Fig. 1. Distribution of VGLUT1 mRNA-containing neurons in
coronal sections of the rat hippocampal formation. A: In a section
processed with antisense RNA probe, VGLUT1 mRNA is expressed in
all glutamatergic neurons of the hippocampal formation, including
the pyramidal cells (P) of CA1-CA3 regions, the granule cells (G) of
dentate gyrus, and mossy cells of the hilus (H). B: In a section
processed with sense RNA probe, faint nonspecific staining is ob-
served in the cell body layers of the hippocampus and dentate gyrus.
C-E: Higher magnifications of the CA3 (C), CA1 (D), and hilar (E)
regions of the section illustrated in A. C: The size and shape of
VGLUT1 mRNA-containing pyramidal cells and of neurons (arrow-
heads) distributed in the stratum lucidum (SL) of CA3 are evident.
D: In CA1, some VGLUT1 mRNA containing neurons (arrowheads)
are present in the stratum radiatum and likely correspond to gluta-
matergic giant cells. E: Numerous large and triangular VGLUT1
mRNA-containing cell bodies (arrowheads) are present in the hilus of
the dentate gyrus. These neurons likely correspond to glutamatergic
hilar mossy cells."
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