All of the evidence provided on Hippocampome.org are quotes from scientific texts.
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EXPRESSION: positive
ANIMAL: mouse
PROTOCOL: immunohistochemistry
Page location: p496, Fig. 2
Linking PMID: 18620078 Linking Quote: Principal neurons identified by the presence of their somata in the principal cell layer, which is densely packed with and nearly homogeneous for the somata of the subregion's principal neurons (Czeh et al., 2013, Acta Biologica Hungarica).
"Fig. 2. Disc1 hippocampal expression from E18-18 weeks. Disc1 is expressed in the hippocampus from embryonic development through adulthood. Both Disc1 (Mid) and (Cterm) antibodies were used to detect Disc1 expression in the mouse hippocampus. At E18 (A-C) and P1 (D-F), Disc1 is expressed throughout the hippocampus, which is still immature in its development. Disc1 is also detected in the stream of migrating granule cells and their precursors moving toward the dentate gyrus (arrows in A and D). From P5 (G-I) through P14 (J-L), Disc1's expression becomes more well-defined in Ammons horn and the dentate gyrus. . . ."
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