All of the evidence provided on Hippocampome.org are quotes from scientific texts.
However, because quoted passages may be difficult to understand in isolation, contextual information and expanded abbreviations set in square brackets have been added for clarity.
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EXPRESSION: negative
ANIMAL: mouse
PROTOCOL: mRNA
Page location: p3, right top
Linking PMID: 15776443 Linking Quote: Principal neurons identified by the presence of their somata in the principal cell layer, which is densely packed with and nearly homogeneous for the somata of the subregion's principal neurons (Czeh et al., 2013, Acta Biologica Hungarica).
"In situ hybridization on serial
thin cryostat sections demonstrates that expression of
genes specific for each hippocampal subregion is nonoverlapping
at dorsal planes of section through the hippocampus.
For example, pyramidal neurons in CA1 express high
levels of Man1a (Fig. 1B,G). Pyramidal neurons in CA3
are uniquely defined by expression of Bok (Fig. 1C,H),
while dentate gyrus granule cells as well as pyramidal
neurons in CA2 are defined by expression of Pcp4 (Fig.
1D,I)."
EXPRESSION: negative
ANIMAL: mouse
PROTOCOL: mRNA
Page location: p4, Fig. 1
Linking PMID: 15776443 Linking Quote: Principal neurons identified by the presence of their somata in the principal cell layer, which is densely packed with and nearly homogeneous for the somata of the subregion's principal neurons (Czeh et al., 2013, Acta Biologica Hungarica).
"Fig. 1. Gene expression defines the boundaries of hippocampal
subregions CA1, CA2, CA3, and the dentate gyrus. In situ hybridization for Man1a [mannosidase 1, alpha] (B,G), Bok [Bcl-2-related ovarian killer protein] (C,H), and Pcp4 [Purkinje cell protein 4] (D,I) on serial coronal sections through the dorsal hippocampus at low magnification (B-D) and high magnification (G-I). Cresyl violet staining is shown on an adjacent serial section (E,J), and bisbenzimide labeling of the same section in panels B and G is shown in panels A and F. Arrowheads in (F-J) delimit the boundaries of CA1, CA2, and CA3. Small arrow in J denotes the hilus of the dentate gyrus."
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