negative inference; confirmed by additional inferences
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EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p1806, right middle
"All PV[parvalbumin]+ neurons [in CA3 and CA1] were positive for the GABA[gamma aminobutyric acid]A receptor [alpha]1 subunit [reference 31] (Fig._5b-d)."
Interpretation notes: Glutamatergic and GABAergic GABAa alpha1- types in CA3 SLM_SR_SL_SP_SO are probably PV- by contrapositive logic
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p555, table 3
"TABLE 3. Distribution of 1 and 2 Adrenergic Receptor Expression in Interneurons in the Adult Rat Hippocampus"
Interpretation notes: Glutamatergic and GABAergic AR-beta1- types in CA3 SR_SLM are probably PV- by contrapositive logic; (n = 5/5)
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p463, Figure 2
Linking PMID: 15224983 Linking Quote: Principal neurons identified by the presence of their somata in the principal cell layer, which is densely packed with and nearly homogeneous for the somata of the subregion's principal neurons (Czeh et al., 2013, Acta Biologica Hungarica).
"FIGURE 2. Distribution of parvalbumin-immunoreactive (PV-IR) cells in the mouse hippocampus. A: In the dentate gyrus, PV-IR
cells could be found within or adjacent to stratum granulosum (arrowheads), occasionally, PV-containing interneurons could be observed in the hilus and stratum moleculare (arrow). Basket-like axon
terminals were found around the immunonegative granule cells (insert). In the inner third of stratum moleculare, a dense cloud of axon
staining could be seen (asterisk). B: In the CA3 region, PV-IR interneurons were present in all layers (arrows and arrowheads), except in
stratum lacunosum-moleculare. Most possessed radially oriented
dendrites (arrowheads), while the others in strata radiatum and oriens
had multipolar dendritic trees with horizontal branches (arrows).
Axon terminals could be seen in clusters around somata (insert), axon
initial segments and proximal basal dendrites of immunonegative
pyramidal cells. C: In the CA1 area, PV-IR interneurons were also
located in strata pyramidale and oriens (arrowheads). Most of them
showed the characteristic features of basket cells or chandelier cells.
Interneurons were rarely present in strata radiatum or lacunosum-moleculare (arrow). PV-IR axon terminals surround the somata and
axon initial segments of the pyramidal cells (insert) and their proximal dendrites."
Interpretation notes: Glutamatergic and GABAergic types in CA3 SLM are negative for PV
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p1220, right top
"In our attempts to identify the CCK[cholecystokinin]-negative subpopulation we found no colocalization of CB1 [cannabinoid type 1] receptor and parvalbumin, as shown previously (Tsou et al., 1999; Katona et al., 1999b, 2000, 2001)."
Interpretation notes: Glutamatergic and GABAergic CB1+ types in CA3 SLM_SR_SL_SP_SO are probably PV-
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p1220, right top
"In our attempts to identify the CCK[cholecystokinin]-negative subpopulation we found no colocalization of CB1 [cannabinoid type 1] receptor and parvalbumin, as shown previously (Tsou et al., 1999; Katona et al., 1999b, 2000, 2001)."
Interpretation notes: Glutamatergic and GABAergic CB1+ types in CA3 SLM_SR_SL_SP_SO are probably PV- by contrapositive logic
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p971, left mid
"Parvalbumin-immunoreactive neurons were seen in strata oriens and pyramidale, but not in strata radiatum and lacunosum-moleculare of the CA1 and CA3, while parvalbumin-immunoreactive fibers were found in all strata, but more concentrated in the stratum pyramidale."
Interpretation notes: Glutamatergic and GABAergic types in CA3 SLM_SR are negative for PV
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p971, left bot
"The cell bodies immunopositive for each marker are distinct (Fig. 3C), indicating that CB1 [cannabinoid] receptors are not expressed on parvalbumin-containing interneurons."
Interpretation notes: Glutamatergic and GABAergic CB1+ types in CA3 SLM_SR_SL_SP_SO are probably PV-
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p971, left bot
"The cell bodies immunopositive for each marker are distinct (Fig. 3C), indicating that CB1 [cannabinoid] receptors are not expressed on parvalbumin-containing interneurons."
Interpretation notes: Glutamatergic and GABAergic CB1+ types in CA3 SLM_SR_SL_SP_SO are probably PV- by contrapositive logic
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p 311, right bottom
"In the case of parvalbumin-VIP [vasoactive intestinal polypeptide] co-localization, only those VIP cells within or close to stratum pyramidale were examined, since parvalbumin cells are absent in other layers. Thus, all VIP-positive cells in the distal part of stratum radiatum or in stratum lacunosum-moleculare are considered parvalbumin-negative by their position. None of the 136 VIP-immunopositive cells near stratum pyramidale in CA1 and the 36 in CA3 showed parvalbumin immunofluorescence (Fig. 8E, F). In addition, 15 large multipolar VIPpositive basket cells were selected from different sections, but those were also negative for parvalbumin. This finding demonstrates that there is a basket cell type different from those containing parvalbumin but which is characterized by the coexistence of VIP and CCK [cholecystokinin]."
Interpretation notes: Glutamatergic and GABAergic types in CA3 SLM_SR are negative for PV
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p841, Table 2
"TABLE 2. Proportion of neurons stained for GABA, calcium-binding proteins
and neuropeptides expressing the a1 subunit-immunoreactivity "
Interpretation notes: Glutamatergic and GABAergic GABAa alpha1- types in CA3 SLM_SR_SL_SP_SO are probably PV- by contrapositive logic
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p128, right top
"In the hippocampus, CCK [cholecystokinin] immunoreactive (CCK-I) terminals were shown to form pericellular baskets around the pyramidal
cell somata and make synaptic contacts on them, and thus some of CCK immunoreactive neurons are considered to be basket cells in this region
[Harris 1985, Hendry 1985, Nunzi 1985]. However, so far our preliminary observations indicated that CCK and PV [parvalbumin] immunoreactivities are not present in the same neuron."
Interpretation notes: Glutamatergic and GABAergic CCK+ types in CA3 SLM_SR_SL_SP_SO are probably PV-
EXPRESSION: negative (inference)
ANIMAL: rat
PROTOCOL: immunohistochemistry
Page location: p128, right top
"In the hippocampus, CCK [cholecystokinin] immunoreactive (CCK-I) terminals were shown to form pericellular baskets around the pyramidal
cell somata and make synaptic contacts on them, and thus some of CCK immunoreactive neurons are considered to be basket cells in this region
[Harris 1985, Hendry 1985, Nunzi 1985]. However, so far our preliminary observations indicated that CCK and PV [parvalbumin] immunoreactivities are not present in the same neuron."
Interpretation notes: Glutamatergic and GABAergic CCK+ types in CA3 SLM_SR_SL_SP_SO are probably PV- by contrapositive logic
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negative inference; confirmed by additional inferences
