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| Morphology |
| Soma | |
| EC:IV | |
| EC:V | |
| EC:VI |
| Axons | |
| SUB:SM | |
| SUB:SP | |
| SUB:PL | |
| EC:IV | |
| EC:V | |
| EC:VI |
| Dendrites | |
| EC:IV | |
| EC:V | |
| EC:VI |
| Representative figure |
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Properties of entorhinal cortex deep layer neurons projecting to the rat dentate gyrus. Gloveli T, Dugladze T, Schmitz D, Heinemann U Eur J Neurosci, 2001 Jan, 13 (2), pages: 413 - 420 PMID: 11168548; DOI: 10.1046/j.0953-816X.2000.01405.x |
 "FIG. 4. Properties of deep layer nonpyramidal projection neurons {EC LIV-VI Deep Multipolar Principal} [in entorhinal cortex]. (Aa) and Ba) Axonal and dendritic morphology of the neurons. For better visualization, the soma and dendrites are drawn in black, the axon is drawn in red. For abbreviations, see Fig. 1A. Open arrows point to the origin of the axons. (Aa) Camera lucida reconstruction of a vertical bipolar cell with a soma located in layer IV. The axon which started from the flat side of the soma reaches the molecular layer of the DG [dentate gyrus]. Note the axonal arborization to the superficial layers." |
| Molecular markers |
| Positive | |
| None known |
| Negative | |
| GABAa\alpha 6 (inference) |
| Mixed expression | |
| NPY (subtypes) | |
| PV (subtypes) | |
| SOM (subtypes) | |
| Sub P (subtypes) | |
| Electrophysiological properties |
| Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max] | |
| Resting membrane potential (Vrest): -59.8±6.8 mV (8); 4 sources (14): [-69 , -59.8] | |
| Input resistance (Rin): 272.3±105.8 MΩ (8); 4 sources (13): [272.3 , 490] | |
| Time constant (τm): 26.6±6.5 ms (8); 4 sources (13): [25 , 36] | |
| Threshold potential (Vthresh): 14.5 mV (1); 4 sources (4): [13 , 36] | |
| Fast afterhyperpolaziring potential amplitude (Fast AHP): 5.7 mV (1); 4 sources (4): [5.7 , 15] | |
| Action potential amplitude (APampl): 80.4 mV (1); 4 sources (4): [69 , 80.4] | |
| Action potential width (APwidth): 1.39±0.6 ms (8); 4 sources (13): [1.39 , 1.7] | |
| Max firing rate (Max F.R.): >70 Hz (1); 1 source | |
| Slow afterhyperpolarizing potential amplitude (Slow AHP): 1.2 mV (1); 2 sources (2): [1.2 , 4.4] | |
| Sag ratio: 0.95 (1); 3 sources (3): [0.85 , 0.95] |
| Notes |
| This cell type represents a merger between EC (+)000333p-SUB 111 multipolar projecting V neurons and EC (+)000033 multipolar-pyramid VI neurons. Excitatory cells (Gloveli 2001 -> GABA negative, projecting, similar EP characteristics to principal neurons; Canto & Witter 201X LEC preprint -> projecting, spiny, "principal"; Canto 2008 -> spiny, projecting). The former 000033 class contains an unspecified axonal projection to the subiculum, and the former 000333 class is known to project to all 3 layers of the subiculum. In 000033, evidence for axons and dendrites in IV is subthreshold, but there is a presence, so an aggressive merger was approved. |
| Firing Pattern |
| Images | |
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| Parameters | View page | |
| ASP. | [Evidence] [Firing Pattern] | |
| NASP | [Evidence] [Firing Pattern] |
| Izhikevich Model |
| Parameters | Single Compartment | Downloads | Simulate |
| subtype: 1 k=0.62;a= 0;b= -22.09;d= 37;C= 240;Vr= -67.73;Vt= -40.44;Vpeak= 21.38;Vmin= -48.28; | Simulate | ||
| subtype: 2 k=0.55;a= 0.003;b= -5.78;d= 51;C= 195;Vr= -67.98;Vt= -44.21;Vpeak= 9.92;Vmin= -51.71; | Simulate | ||
| subtype: 3 k=0.63;a= 0.003;b= -4.6;d= 82;C= 459;Vr= -64.84;Vt= -46.39;Vpeak= 12.95;Vmin= -45.5; | Simulate | ||
| subtype: 4 k=1.8;a= 0.002;b= 2.58;d= 7;C= 476;Vr= -64.72;Vt= -58.76;Vpeak= -4.01;Vmin= -59.31; | Simulate |
| Images | |
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| ModelDB Model |
| Model Accession Number | PubMed ID |
| Sources of Input |
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| Targets of Output |
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| Oscillation Phase Locking |
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