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| Morphology |
| Soma | |
| EC:III |
| Axons | |
| EC:I | |
| EC:II | |
| EC:III |
| Dendrites | |
| EC:III | |
| EC:IV | |
| EC:V |
| Representative figure |
|
Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy. Kumar SS, Buckmaster PS J Neurosci, 2006 Apr 26, 26 (17), pages: 4613 - 4623 PMID: 16641241; DOI: 10.1523/JNEUROSCI.0064-06.2006 |
 "Figure 4. Anatomical and electrophysiological features of the two dominant types of inhibitory interneurons in layer III of the medial entorhinal cortex and their excitatory synaptic drive. A, Typical biocytin-labeled type I {MEC LIII Superficial Multipolar Interneuron} and type II {MEC LIII Multipolar Interneuron} interneurons showing differences in the orientation of their dendrites (thicker branches). The axon projections (thinner branches) of the two cell types are different: confined to the vicinity of the cell body and extending into layer II for type I and projecting to and ramifying in layer I for type II (black arrowheads). Magnified views of the boxed regions are shown on the right and in insets (top) of the respective figures, illustrating dendritic spines (white arrowheads) on type II interneurons but not type I interneurons. Differences in the shape of the cell bodies are subtle but distinguishable when examined with infrared differential-interference contrast optics (top inset)." |
| Molecular markers |
| Positive | |
| None known |
| Negative | |
| GABAa\alpha 6 (inference) |
| Mixed expression | |
| None known |
| Electrophysiological properties |
| Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max] | |
| Resting membrane potential (Vrest): -54±5.5 mV (25); 1 source | |
| Input resistance (Rin): 382±235.0 MΩ (25); 1 source | |
| Threshold potential (Vthresh): 27 mV (1); 1 source | |
| Fast afterhyperpolaziring potential amplitude (Fast AHP): 38±5.0 mV (11); 1 source | |
| Action potential amplitude (APampl): 87.8 mV (1); 1 source | |
| Action potential width (APwidth): 0.4 ms (11); 1 source | |
| Slow afterhyperpolarizing potential amplitude (Slow AHP): 3.5 mV (1); 1 source | |
| Sag ratio: 0.8 (1); 1 source |
| Notes |
| Borderline Dend in L5 |
| Firing Pattern |
| Images | |
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| Parameters | View page | |
| NASP | [Evidence] [Firing Pattern] |
| Izhikevich Model |
| Parameters | Single Compartment | Downloads | Simulate |
| subtype: 1 k=2.32;a= 0.003;b= 12.27;d= -2;C= 115;Vr= -57.15;Vt= -50.75;Vpeak= 2.43;Vmin= -60.23; | Simulate |
| Images | |
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| ModelDB Model |
| Model Accession Number | PubMed ID |
| Sources of Input |
| Targets of Output |
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| Oscillation Phase Locking |
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