MEC LV Superficial Pyramidal
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
MEC (e)213330 LV Superficial Pyramidal S081906:Glutamatergic Deep:LIV-VI:EC

Name derivation
This is the cited name.

Synonym(s)
MEC LV superficial pyramidal neuron

List of articles
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Canto CB  (2012) Hippocampus
Cellular properties of principal neurons in the rat entorhinal cortex. II. The medial entorhinal cortex.
Canto CB, Witter MP.
Hippocampus, 2012 Jun, 22 (6), Pages: 1277 - 1299
PMID: 22161956; DOI: 10.1002/hipo.20993
Tags: morphology, membrane biophysics, firing patterns, synapse probabilities

Supplemental PMIDs
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List of Hippocampome.org to NeuroMorpho.Org mappings
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  • Rice-Baylor
    • AR-1-20-04-A (fits the general description of "MEC LV Pyramidal" or "EC LV Deep Pyramidal" or "MEC LV Superficial Pyramidal" or "MEC LV Multipolar-Pyramidal" or "MEC LV-VI Pyramidal-Polymorphic" or "EC LIV-V Pyramidal-Horizontal" based on the distribution of axons and dendrites)
    • AR-1-20-04-B (fits the general description of "EC LV Deep Pyramidal" or "MEC LV Superficial Pyramidal" or "EC LIV-V Pyramidal-Horizontal" based on the distribution of axons and dendrites)
    • AR-1-20-04-C (fits the general description of "MEC LV Superficial Pyramidal" or "EC LIV-V Pyramidal-Horizontal" based on the distribution of axons and dendrites)
    • more ...

    • Morphology
    Soma
    EC:V
    Axons
    EC:II
    EC:III
    EC:IV
    EC:V
    Dendrites
    EC:I
    EC:III
    EC:IV
    EC:V

    Molecular markers
    Positive
    None known
    Negative
    GABAa\alpha 6 (inference)
    Mixed expression
    None known

    Electrophysiological properties
    Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max]

    Resting membrane potential (Vrest): [-69.0, -64.0] mV (2); 1 source
    Input resistance (Rin): 605 MΩ (72); 1 source
    Time constant (τm): 37±17.0 ms (72); 1 source
    Threshold potential (Vthresh): 28.7 mV (1); 1 source
    Fast afterhyperpolaziring potential amplitude (Fast AHP): 7.75 mV (1); 1 source
    Action potential amplitude (APampl): 61 mV (72); 1 source
    Action potential width (APwidth): 1.8 ms (72); 1 source
    Sag ratio: 0.86 (72); 1 source

    Notes
    Rejected merger with LEC (+)113330 multipolar neurons 1 III (MPN 1 III), since these cells have "no main apical dendrite traveling up to the pia" and, for MPN 1 III, "Within LI the diameter of the apical dendritic tree can be up to 400 microm." Likely excitatory cells (Canto 201X MEC preprint -> "principal," spiny to sparsely spiny).

    Firing Pattern
    Images
    Image MissingImage MissingImage MissingImage MissingImage Missing
    Parameters View page
    ASP. [Evidence] [Firing Pattern]
    ASP.SLN [Evidence] [Firing Pattern]
    NASP [Evidence] [Firing Pattern]

    Izhikevich Model
    Parameters Single Compartment Downloads Simulate
    subtype: 1 k=0.21;a= 0;b= -16.14;d= 19;C= 157;Vr= -66.55;Vt= -32.89;Vpeak= 13.4;Vmin= -51.2; Simulate
    subtype: 2 k=0.36;a= 0.001;b= -3.24;d= 13;C= 131;Vr= -68.47;Vt= -35.24;Vpeak= 10.74;Vmin= -53.2; Simulate
    subtype: 3 k=0.4;a= 0.009;b= 5.29;d= -12;C= 56;Vr= -66.32;Vt= -31.51;Vpeak= 13.08;Vmin= -51.3; Simulate
    Images
    Image MissingImage MissingImage Missing
    ModelDB Model
    Model Accession Number PubMed ID

    Sources of Input
    Known sources
    Excitatory or Inhibitory
    none known

    Potential sources
    Excitatory or Inhibitory
    CA1 Pyramidal
    CA1 Deep Pyramidal
    CA1 Superficial Pyramidal
    Sub EC-Projecting Pyramidal
    EC LI-II Multipolar-Pyramidal
    EC LI-II Pyramidal-Fan
    MEC LII Oblique Pyramidal
    MEC LII Stellate
    MEC LII-III Pyramidal-Multiform
    EC LII-III Pyramidal-Tripolar
    MEC LIII Multipolar Principal
    EC LIII Small Pyramidal
    MEC LIII Complex Pyramidal
    MEC LIII Bipolar Complex Pyramidal
    EC LIII Pyramidal
    EC LIII Stellate
    EC LIII-V Bipolar Pyramidal
    EC LIV-V Pyramidal-Horizontal
    EC LIV-VI Deep Multipolar Principal
    MEC LV Multipolar-Pyramidal
    MEC LV Principal*
    MEC LV Pyramidal
    EC LV Deep Pyramidal
    MEC LV Superficial Pyramidal
    MEC LI-II Polar Interneuron*
    MEC LII Basket
    EC LIII Bipolar Interneuron*
    MEC LIII Multipolar Interneuron
    MEC LIII Superficial Multipolar Interneuron
    MEC LI Neurogliaform*
    EC LII-III Superficial Polymorphic Interneuron*
    EC LIII Pyramidal-Looking Interneuron
    MEC LIII Superficial Trilayered Interneuron

    Potential sources known to be avoided
    Excitatory or Inhibitory
    LEC LIII Multipolar Principal
    LEC LIII Complex Pyramidal
    LEC LVI Multipolar-Pyramidal
    LEC LIII Multipolar Interneuron

    Targets of Output
    Known targets
    Excitatory or Inhibitory
    none known

    Potential targets
    Excitatory or Inhibitory
    EC LI-II Multipolar-Pyramidal
    EC LI-II Pyramidal-Fan
    MEC LII Oblique Pyramidal
    MEC LII Stellate
    MEC LII-III Pyramidal-Multiform
    EC LII-III Pyramidal-Tripolar
    MEC LIII Multipolar Principal
    EC LIII Small Pyramidal
    MEC LIII Complex Pyramidal
    MEC LIII Bipolar Complex Pyramidal
    EC LIII Pyramidal
    EC LIII Stellate
    EC LIII-V Bipolar Pyramidal
    EC LIV-V Pyramidal-Horizontal
    EC LIV-VI Deep Multipolar Principal
    MEC LV Multipolar-Pyramidal
    MEC LV Principal*
    MEC LV Pyramidal
    EC LV Deep Pyramidal
    MEC LV Superficial Pyramidal
    MEC LV-VI Pyramidal-Polymorphic
    MEC LI-II Polar Interneuron*
    EC LII Axo-axonic
    MEC LII Basket
    EC LII Basket-Neurogliaform
    EC LIII Bipolar Interneuron*
    MEC LIII Multipolar Interneuron
    MEC LIII Superficial Multipolar Interneuron
    EC LII-III Superficial Polymorphic Interneuron*
    EC LIII Pyramidal-Looking Interneuron
    MEC LIII Superficial Trilayered Interneuron

    Potential targets known to be avoided
    Excitatory or Inhibitory
    LEC LIII Multipolar Principal
    LEC LIII Complex Pyramidal
    LEC LVI Multipolar-Pyramidal
    LEC LIII Multipolar Interneuron

    Oscillation Phase Locking
    Category
    Value