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* indicates new v2.0 neuron type Name Supertype (ID:Family:Type:Subregion) MEC (e)313300 LIII Complex Pyramidal S071806:Glutamatergic III:LIII:EC Name derivation This is the cited name. Synonym(s) MEC LIII complex pyramidal neuron List of articles Click here to view the list Canto CB  (2012) Hippocampus Cellular properties of principal neurons in the rat entorhinal cortex. II. The medial entorhinal cortex. Canto CB, Witter MP. Hippocampus, 2012 Jun, 22 (6), Pages: 1277 - 1299 PMID: 22161956; DOI: 10.1002/hipo.20993 Tags: morphology, membrane biophysics, firing patterns, synapse probabilities

Morphology

Soma
	EC:III

Axons
	EC:I
	EC:II
	EC:III
	EC:IV

Dendrites
	EC:I
	EC:III
	EC:IV

Molecular markers

Positive
	None known

Negative
	GABAa\alpha 6 (inference)

Mixed expression
	None known

Electrophysiological properties

	Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max]
	Resting membrane potential (Vrest): [-63.0, -59.0] mV (2); 1 source
	Input resistance (Rin): 468±174.4 MΩ (76); 1 source
	Time constant (τm): 43.5±17.4 ms (76); 1 source
	Threshold potential (Vthresh): 19.5 mV (1); 1 source
	Fast afterhyperpolaziring potential amplitude (Fast AHP): 12.7 mV (1); 1 source
	Action potential amplitude (APampl): 76±8.7 mV (76); 1 source
	Action potential width (APwidth): 1.45±4.4 ms (76); 1 source
	Sag ratio: 0.86 (1); 1 source

Notes

Excitatory because they have spiny dendrites.

Firing Pattern

Images

Parameters		View page
	ASP.NASP	[Evidence] [Firing Pattern]
	NASP	[Evidence] [Firing Pattern]
	RASP.ASP.	[Evidence] [Firing Pattern]

Izhikevich Model

Parameters	Single Compartment	Downloads	Simulate
	subtype: 1 k=0.95;a= 0.028;b= -21.99;d= 805;C= 407;Vr= -59.01;Vt= -39.01;Vpeak= 21.51;Vmin= -38.58;	[FitFiles][CSV][XPP][Ensemble]	Simulate
	subtype: 2 k=0.53;a= 0.004;b= -0.58;d= 79;C= 749;Vr= -63.59;Vt= -38.65;Vpeak= 18.15;Vmin= -43.59;	[FitFiles][CSV][XPP][Ensemble]	Simulate
	subtype: 3 k=0.91;a= 0.069;b= 4.08;d= 45;C= 115;Vr= -58.98;Vt= -35.21;Vpeak= 21.99;Vmin= -38.94;	[FitFiles][CSV][XPP][Ensemble]	Simulate

Images

ModelDB Model

Model Accession Number

PubMed ID

Sources of Input

Known sources Excitatory or Inhibitory none known

Potential sources Excitatory or Inhibitory Sub EC-Projecting Pyramidal EC LI-II Multipolar-Pyramidal EC LI-II Pyramidal-Fan MEC LII Oblique Pyramidal MEC LII Stellate MEC LII-III Pyramidal-Multiform EC LII-III Pyramidal-Tripolar MEC LIII Multipolar Principal EC LIII Small Pyramidal MEC LIII Complex Pyramidal MEC LIII Bipolar Complex Pyramidal EC LIII Pyramidal EC LIII Stellate EC LIII-V Bipolar Pyramidal EC LIV-VI Deep Multipolar Principal MEC LV Multipolar-Pyramidal MEC LV Pyramidal MEC LV Superficial Pyramidal MEC LI-II Polar Interneuron* MEC LII Basket EC LIII Bipolar Interneuron* MEC LIII Multipolar Interneuron MEC LIII Superficial Multipolar Interneuron MEC LI Neurogliaform* EC LII-III Superficial Polymorphic Interneuron* EC LIII Pyramidal-Looking Interneuron MEC LIII Superficial Trilayered Interneuron

Potential sources known to be avoided Excitatory or Inhibitory LEC LIII Multipolar Principal LEC LIII Complex Pyramidal LEC LVI Multipolar-Pyramidal LEC LIII Multipolar Interneuron

Targets of Output

Known targets Excitatory or Inhibitory none known

Potential targets Excitatory or Inhibitory EC LI-II Multipolar-Pyramidal EC LI-II Pyramidal-Fan MEC LII Oblique Pyramidal MEC LII Stellate MEC LII-III Pyramidal-Multiform EC LII-III Pyramidal-Tripolar MEC LIII Multipolar Principal EC LIII Small Pyramidal MEC LIII Complex Pyramidal MEC LIII Bipolar Complex Pyramidal EC LIII Pyramidal EC LIII Stellate EC LIII-V Bipolar Pyramidal EC LIV-V Pyramidal-Horizontal EC LIV-VI Deep Multipolar Principal MEC LV Multipolar-Pyramidal MEC LV Principal* MEC LV Pyramidal EC LV Deep Pyramidal MEC LV Superficial Pyramidal MEC LI-II Polar Interneuron* EC LII Axo-axonic MEC LII Basket EC LII Basket-Neurogliaform EC LIII Bipolar Interneuron* MEC LIII Multipolar Interneuron MEC LIII Superficial Multipolar Interneuron MEC LI Neurogliaform* EC LII-III Superficial Polymorphic Interneuron* EC LIII Pyramidal-Looking Interneuron MEC LIII Superficial Trilayered Interneuron

Potential targets known to be avoided Excitatory or Inhibitory LEC LIII Multipolar Principal LEC LIII Complex Pyramidal LEC LIII Multipolar Interneuron

Oscillation Phase Locking

Category

Value