CA1 Interneuron Specific R-O
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
CA1 (i)0221 Interneuron Specific R-O S091204:Interneuron Specific:IS:CA1

Name derivation
This cell is verified to preferentially target non-principal cells. Although more politically loaded, the phrase "interneuron specific" is more compact than "non-principal cell-specific" and is more commonly found in the cited literature. The modifier is a variant of "O-LM" because the dendrites are in SR and the axons project to SO. CA1 clarifies the subregion of origin, since the name is otherwise generic.

Synonym(s)
CA1 vasoactive intestinal peptide-immunoreactive interneuron
CA1 VIP-containing interneuron
CA1 VIP-positive cell
CA1 VIP-positive interneuron projecting to the O/A border
CA1 VIP+/CR+/nNOS+ interneuron
CA1 VIP+/nNOS+ cell
CA1 VIP+/nNOS+ interneuron

List of articles
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Acsady L  (1996) Neuroscience
Correlated morphological and neurochemical features identify different subsets of vasoactive intestinal polypeptide-immunoreactive interneurons in rat hippocampus.
Acsady L, Arabadzisz D, Freund TF.
Neuroscience, 1996 Jul, 73 (2), Pages: 299 - 315
PMID: 8783251; DOI: 10.1016/0306-4522(95)00610-9
Tags: morphology, marker, connectivity, synapse probabilities
Tricoire L  (2010) J Neurosci
Common origins of hippocampal Ivy and nitric oxide synthase expressing neurogliaform cells.
Tricoire L, Pelkey KA, Daw MI, Sousa VH, Miyoshi G, Jeffries B, Cauli B, Fishell G, McBain CJ.
J Neurosci, 2010 Feb 10, 30 (6), Pages: 2165 - 2176
PMID: 20147544; DOI: 10.1523/JNEUROSCI.5123-09.2010
Tags: morphology, marker, synapse probabilities
Tricoire L  (2012) Front Neural Circuits
Neuronal nitric oxide synthase expressing neurons: a journey from birth to neuronal circuits.
Tricoire L, Vitalis T.
Front Neural Circuits, 2012, 6, Pages: 82 -
PMID: 23227003; DOI: 10.3389/fncir.2012.00082
Tags: morphology, connectivity, synapse probabilities


Morphology
Soma
CA1:SP
Axons
CA1:SO
Dendrites
CA1:SR
CA1:SP

Molecular markers
Positive
CR
nNOS
VIP
Negative
AR-beta1 (inference)
AR-beta2 (inference)
CB (confirmed by inference)
CB1 (multiple confirming inferences)
CCK (confirmed by inference)
Chrna2 (inference)
GABAa\alpha 6 (inference)
Gaba-a-alpha (multiple confirming inferences)
mGluR1a (inference)
MOR (multiple confirming inferences)
PV (confirmed by inference)
SATB1 (inference)
SOM (multiple confirming inferences)
vGluT3 (multiple confirming inferences)
Mixed expression
None known

Electrophysiological properties
None known


Firing Pattern
Images
No image is associated with this neuron
Parameters
No parameter associated with this neuron
ModelDB Model
Model Accession Number PubMed ID

Sources of Input
Known sources
Excitatory or Inhibitory
CA1 Interneuron Specific LM-R

Potential sources
Excitatory or Inhibitory
CA3 Pyramidal
CA3c Pyramidal
CA3c Umbrella Pyramidal*
CA3 Trilaminar
CA2 Pyramidal
CA2 Wide-Arbor Basket
CA2 Bistratified
CA1 Back-Projection
CA1 Basket
CA1 Horizontal Basket
CA1 R-P Basket*
CA1 Trilayer Basket*
CA1 Vertical Basket*
CA1 Basket CCK+
CA1 Horizontal Basket CCK+*
CA1 Trilayer Basket CCK+*
CA1 Bistratified
CA1 Hippocampo-subicular Projecting ENK+
CA1 Ivy
CA1 LMR
CA1 LMR-R*
CA1 Interneuron Specific LMR-R
CA1 LMR Projecting
CA1 O-LMR
CA1 Recurrent O-LMR*
CA1 Interneuron Specific O-R
CA1 O-RP*
CA1 Oriens/Alveus
CA1 Oriens-Bistratified
CA1 Oriens-QuadA Projecting
CA1 O-RPO*
CA1 QuadD-RP*
CA1 Quadrilaminar
CA1 R-Receiving Apical-Targeting
CA1 R-RO*
CA1 R-RP*
CA1 Radiatum
CA1 Interneuron Specific RO-R*
CA1 RO-RP*
CA1 RP-RPO*
CA1 Schaffer Collateral-Associated
CA1 Schaffer Collateral-Correlated*
CA1 Schaffer Collateral-Receiving R-Targeting
CA1 Trilaminar
CA1 Radial Trilaminar
Sub CA1-Projecting Pyramidal
EC LIII Small Pyramidal
EC LIII Pyramidal

Potential sources known to be avoided
Excitatory or Inhibitory
CA1 Axo-axonic
CA1 Horizontal Axo-axonic

Targets of Output
Known targets
Excitatory or Inhibitory
CA1 O-LM

Potential targets
Excitatory or Inhibitory
CA1 Axo-axonic
CA1 Horizontal Axo-axonic
CA1 Back-Projection
CA1 Basket
CA1 Horizontal Basket
CA1 Trilayer Basket*
CA1 Basket CCK+
CA1 Horizontal Basket CCK+*
CA1 Trilayer Basket CCK+*
CA1 Bistratified
CA1 RO-receiving CA3-targeting*
CA1 Hippocampo-subicular Projecting ENK+
CA1 Ivy
CA1 Interneuron Specific LMO-O
CA1 Recurrent O-LM
CA1 O-LMR
CA1 Recurrent O-LMR*
CA1 Interneuron Specific O-R
CA1 O-RP*
CA1 Interneuron Specific O-Targeting QuadD
CA1 Oriens/Alveus
CA1 Oriens-Bistratified
CA1 Oriens-QuadA Projecting
CA1 OR-LM
CA1 O-RPO*
CA1 Perforant Path-Associated QuadD
CA1 QuadD-RP*
CA1 Quadrilaminar
CA1 Interneuron Specific RO-O
CA1 Interneuron Specific RO-R*
CA1 RO-RP*
CA1 Schaffer Collateral-Correlated*
CA1 Schaffer Collateral-Receiving R-Targeting
CA1 SO-SO
CA1 SO-SO Projecting*
CA1 Trilaminar
CA1 Radial Trilaminar

Potential targets known to be avoided
Excitatory or Inhibitory
CA1 Pyramidal
CA1 Deep Pyramidal
CA1 Superficial Pyramidal

Oscillation Phase Locking
Category
Value