CA1 Recurrent O-LM
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
CA1 (i)1003 Recurrent O-LM S121404:O-LM Family:O-LM-like:CA1

Name derivation
This is the most well known name in the cited literature. This O-LM cell has a recurrent collateral that re-invades SO that distinguishes it from the canonical CA1 O-LM cell and from the variant with an axon invading SR. CA1 distinguishes these cells from O-LM cells in other subregions. O-LM stands for "Oriens (dendrites) - Lacunosum-Moleculare (axons)."

Synonym(s)
CA1 horizontal cell
CA1 O-A interneurone
CA1 O-LM cell
CA1 O-LM interneuron
CA1 OLM cell
CA1 oriens-lacunosum moleculare interneuron

List of articles
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Ali AB  (1998) J Physiol
Facilitating pyramid to horizontal oriens-alveus interneurone inputs: dual intracellular recordings in slices of rat hippocampus.
Ali AB, Thomson AM.
J Physiol, 1998 Feb 15, 507 ( Pt 1), Pages: 185 - 199
PMID: 9490837; DOI: 10.1111/j.1469-7793.1998.185bu.x
Tags: morphology, membrane biophysics, connectivity, firing patterns, synapse probabilities
Kispersky TJ  (2012) J Neurosci
Spike resonance properties in hippocampal O-LM cells are dependent on refractory dynamics.
Kispersky TJ, Fernandez FR, Economo MN, White JA.
J Neurosci, 2012 Mar 14, 32 (11), Pages: 3637 - 3651
PMID: 22423087; DOI: 10.1523/JNEUROSCI.1361-11.2012
Tags: morphology, synapse probabilities
Losonczy A  (2002) J Physiol
Cell type dependence and variability in the short-term plasticity of EPSCs in identified mouse hippocampal interneurones.
Losonczy A, Zhang L, Shigemoto R, Somogyi P, Nusser Z.
J Physiol, 2002 Jul 1, 542 (Pt 1), Pages: 193 - 210
PMID: 12096061; DOI: 10.1113/jphysiol.2002.020024
Tags: morphology, marker, connectivity, synapse probabilities
Svoboda KR  (1999) J Neurosci
Opioid receptor subtype expression defines morphologically distinct classes of hippocampal interneurons.
Svoboda KR, Adams CE, Lupica CR.
J Neurosci, 1999 Jan 1, 19 (1), Pages: 85 - 95
PMID: 9870941
Tags: morphology, connectivity, synapse probabilities
Tricoire L  (2011) J Neurosci
A blueprint for the spatiotemporal origins of mouse hippocampal interneuron diversity.
Tricoire L, Pelkey KA, Erkkila BE, Jeffries BW, Yuan X, McBain CJ.
J Neurosci, 2011 Jul 27, 31 (30), Pages: 10948 - 10970
PMID: 21795545; DOI: 10.1523/JNEUROSCI.0323-11.2011
Tags: morphology, marker, synapse probabilities

Supplemental PMIDs
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List of Hippocampome.org to NeuroMorpho.Org mappings
Click here to view the list of mappings
  • McBain
  • White

    • Morphology
    Soma
    CA1:SO
    Axons
    CA1:SLM
    CA1:SO
    Dendrites
    CA1:SO

    Molecular markers
    Positive
    AR-beta1 (inference)
    CB
    mGluR1
    mGluR1a (confirmed by inference)
    NPY
    SOM (confirmed by inference)
    Negative
    5HT-3 (confirmed by inference)
    AR-beta2 (multiple confirming inferences)
    CB1 (multiple confirming inferences)
    CCK (confirmed by inference)
    CoupTF II
    CR (confirmed by inference)
    ENK (confirmed by inference)
    ErbB4 (multiple confirming inferences)
    GABAa\alpha 6 (inference)
    Gaba-a-alpha (multiple confirming inferences)
    mGluR5 (multiple confirming inferences)
    MOR (multiple confirming inferences)
    nNOS
    PV (confirmed by inference)
    vGluT3 (confirmed by inference)
    VIP (confirmed by inference)
    Mixed expression
    None known

    Electrophysiological properties
    Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max]

    Resting membrane potential (Vrest): [-85.0, -65.0] mV (2); 1 source
    Input resistance (Rin): 70±13.72 MΩ (8); 1 source
    Time constant (τm): 12.8±1.5 ms (8); 1 source
    Threshold potential (Vthresh): 25 mV (1); 1 source
    Fast afterhyperpolaziring potential amplitude (Fast AHP): 16.1±10.7 mV (8); 1 source
    Action potential amplitude (APampl): 58.75±7.2 mV (8); 1 source
    Action potential width (APwidth): 0.6±0.3 ms (8); 1 source
    Max firing rate (Max F.R.): >150 Hz (1); 1 source
    Slow afterhyperpolarizing potential amplitude (Slow AHP): 5 mV (1); 1 source
    Sag ratio: 0.62 (1); 1 source


    Firing Pattern
    Images
    Image MissingImage MissingImage Missing
    Parameters View page
    ASP. [Evidence] [Firing Pattern]
    NASP [Evidence] [Firing Pattern]

    Izhikevich Model
    Parameters Single Compartment Downloads Simulate
    subtype: 1 k=0.64;a= 0.001;b= 1.93;d= 20;C= 210;Vr= -68.46;Vt= -40.03;Vpeak= 24.6;Vmin= -68.06; Simulate
    Images
    Image Missing
    ModelDB Model
    Model Accession Number PubMed ID

    Sources of Input
    Known sources
    Excitatory or Inhibitory
    CA1 Pyramidal

    Potential sources
    Excitatory or Inhibitory
    CA3 Pyramidal
    CA3c Pyramidal
    CA3 Trilaminar
    CA2 Pyramidal
    CA2 Bistratified
    CA1 Deep Pyramidal
    CA1 Superficial Pyramidal
    CA1 Radiatum Giant
    CA1 Back-Projection
    CA1 Bistratified
    CA1 Hippocampo-subicular Projecting ENK+
    CA1 Ivy
    CA1 Interneuron Specific LMO-O
    CA1 Interneuron Specific LMR-O*
    CA1 Recurrent O-LM
    CA1 Recurrent O-LMR*
    CA1 Interneuron Specific O-Targeting QuadD
    CA1 Oriens/Alveus
    CA1 Oriens-Bistratified
    CA1 Oriens-QuadA Projecting
    CA1 O-RPO*
    CA1 Quadrilaminar
    CA1 Interneuron Specific R-O
    CA1 R-RO*
    CA1 Interneuron Specific RO-O
    CA1 RP-RPO*
    CA1 Schaffer Collateral-Associated
    CA1 Schaffer Collateral-Correlated*
    CA1 SO-SO
    CA1 SO-SO Projecting*
    CA1 Trilaminar
    CA1 Radial Trilaminar
    EC LIII Small Pyramidal
    EC LIII Pyramidal

    Potential sources known to be avoided
    Excitatory or Inhibitory
    none known

    Targets of Output
    Known targets
    Excitatory or Inhibitory
    none known

    Potential targets
    Excitatory or Inhibitory
    CA1 Pyramidal
    CA1 Deep Pyramidal
    CA1 Superficial Pyramidal
    CA1 Cajal-Retzius
    CA1 Local-Projecting Cajal-Retzius*
    CA1 Radiatum Giant
    CA1 Axo-axonic
    CA1 Horizontal Axo-axonic
    CA1 Back-Projection
    CA1 Basket
    CA1 Horizontal Basket
    CA1 Trilayer Basket*
    CA1 Vertical Basket*
    CA1 Basket CCK+
    CA1 Horizontal Basket CCK+*
    CA1 Trilayer Basket CCK+*
    CA1 Bistratified
    CA1 RO-receiving CA3-targeting*
    CA1 Hippocampo-subicular Projecting ENK+
    CA1 Ivy
    CA1 Interneuron Specific LM-R
    CA1 Interneuron Specific LMO-O
    CA1 LMR
    CA1 LMR-LM*
    CA1 Interneuron Specific LMR-O*
    CA1 LMR-R*
    CA1 Interneuron Specific LMR-R
    CA1 LMR Projecting
    CA1 Neurogliaform
    CA1 Neurogliaform Projecting
    CA1 O-LM
    CA1 Recurrent O-LM
    CA1 O-LMR
    CA1 Recurrent O-LMR*
    CA1 Interneuron Specific O-R
    CA1 O-RP*
    CA1 Interneuron Specific O-Targeting QuadD
    CA1 Oriens/Alveus
    CA1 Oriens-Bistratified
    CA1 Oriens-QuadA Projecting
    CA1 OR-LM
    CA1 O-RPO*
    CA1 Perforant Path-Associated
    CA1 Perforant Path-Associated QuadD
    CA1 QuadD-RP*
    CA1 Quadrilaminar
    CA1 Interneuron Specific RO-O
    CA1 Interneuron Specific RO-R*
    CA1 RO-RP*
    CA1 Schaffer Collateral-Associated
    CA1 Schaffer Collateral-Correlated*
    CA1 Schaffer Collateral-Receiving R-Targeting
    CA1 SO-SO
    CA1 SO-SO Projecting*
    CA1 Trilaminar
    CA1 Radial Trilaminar

    Potential targets known to be avoided
    Excitatory or Inhibitory
    none known

    Oscillation Phase Locking
    Category
    Value