CA1 Schaffer Collateral-Correlated*
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
CA1 (i)0303 Schaffer Collateral-Correlated* S131504:Collateral-related:RO-targeting:CA1

Name derivation
The name describes the locations of both the axons and the dendrites.

Synonym(s)
CA1 type I CB-IR interneuron
CA1 O-OR
CA1 R-OR

List of articles
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Cossart R  (2006) Hippocampus
Interneurons targeting similar layers receive synaptic inputs with similar kinetics
Cossart R, Petanjek Z, Dumitriu D, Hirsch JC, Ben-Ari Y, Esclapez M, Bernard C.
Hippocampus, 2006, 16 (4), Pages: 408 - 420
PMID: 16435315; DOI: 10.1002/hipo.20169
Tags: morphology
Gulyas AI  (1996) Hippocampus
Pyramidal cell dendrites are the primary targets of calbindin D28k-immunoreactive interneurons in the hippocampus.
Gulyas AI, Freund TF.
Hippocampus, 1996, 6 (5), Pages: 525 - 534
PMID: 8953305; DOI: 10.1002/(SICI)1098-1063(1996)6:5<525::AID-HIPO5>3.0.CO;2-H
Tags: morphology, marker, connectivity, synapse probabilities

Supplemental PMIDs
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List of Hippocampome.org to NeuroMorpho.Org mappings
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  • Esclapez

  • Morphology
    Soma
    CA1:SR
    CA1:SP
    CA1:SO
    Axons
    CA1:SR
    CA1:SO
    Dendrites
    CA1:SR
    CA1:SO

    Molecular markers
    Positive
    CB
    Negative
    CR (inference)
    ENK (multiple confirming inferences)
    GABAa\alpha 6 (inference)
    Gaba-a-alpha (multiple confirming inferences)
    PV (multiple confirming inferences)
    vGluT3 (inference)
    VIP (multiple confirming inferences)
    Mixed expression
    None known

    Electrophysiological properties
    None known

    Notes

    CA1 (i)0303 Schaffer Collateral-Correlated (SCC) cells [4048]

    Related types: CA1 (i)2333 Radial Trilaminar
    CA1 (i)2311 Schaffer Collateral-Associated
    CA1 (i)0333 Ivy
    CA1 (i)0333 Bistratified
    CA1 (i)0331 RP-RPO
    CA1 (i)0322 Schaffer Collateral-Receiving R-Targeting
    CA1 (i)0313p Hippocampo-subicular Projecting ENK+
    CA1 (i)0301 R-RO
    CA1 (i)0113p Trilaminar

    Notes:

    N = 5.

    I do not approve this type. The neuron on page five could be a 0302, and the one on page 7 a 2333 or 2313. - CW 02/18/2015

    I agree with Charise and freezing these separately. I do think that the neuron on pg 5 is 0303, but I canā??t ignore D:SLM on pg 7. - CLR 02/18/2015

    The McMahon cell has been reinterpreted as 2333 and is now considered to be a supplement to that cell type. - 07/21/2015

    Cossart 2006 was added. According to Cossart interpretation rules, there are only axonal connections in SR and SO, none in SP. - 07/21/2015

    Is the Gulyas cell to be a 0303 or a 0302? I vote 0303. - DWW 09/10/2015

    0303 - CW 09/16/2015

    0303. - CLR 10/10/2015

    How different are these from existing 333 type? - GAA 11/29/2015

    According to Cossart, there is a significant difference. Cossart explicitly describes cells that make contact in SP and separates them from a set that clearly does not make contact in SP. However, both the 0333 and 0303 patterns are currently under proposal for being in the same interneuron supertype grouping. - DWW 04/20/2016

    ro-ro?! Ok (sigh) add related types! (BC?) - GAA 05/25/2016

    How about Schaffer Collateral-Correlated (SCC) cells? We already have 2311 Schaffer Collateral-Associated cells and 0322 Schaffer Collateral-Receiving cells - DWW 05/25/2016

    I suggest Bistratified-OR. - KM 05/25/2016

    I am in agreement with keeping these two types (CA1 BiC and SCC) separated based on Cossart et al.'s determination. - JDK 11/03/2021
    After re-review, I still support these two neuron types be separated based on Cossart et al.'s determination. - JDK 11/22/2021

    Firing Pattern
    Images
    No image is associated with this neuron
    Parameters
    No parameter associated with this neuron
    ModelDB Model
    Model Accession Number PubMed ID

    Sources of Input
    Known sources
    Excitatory or Inhibitory
    none known

    Potential sources
    Excitatory or Inhibitory
    CA3 Pyramidal
    CA3c Pyramidal
    CA3c Umbrella Pyramidal*
    CA3 Trilaminar
    CA2 Pyramidal
    CA2 Bistratified
    CA1 Pyramidal
    CA1 Deep Pyramidal
    CA1 Superficial Pyramidal
    CA1 Radiatum Giant
    CA1 Back-Projection
    CA1 Bistratified
    CA1 Hippocampo-subicular Projecting ENK+
    CA1 Ivy
    CA1 Interneuron Specific LM-R
    CA1 Interneuron Specific LMO-O
    CA1 LMR
    CA1 Interneuron Specific LMR-O*
    CA1 LMR-R*
    CA1 Interneuron Specific LMR-R
    CA1 LMR Projecting
    CA1 Recurrent O-LM
    CA1 O-LMR
    CA1 Recurrent O-LMR*
    CA1 Interneuron Specific O-R
    CA1 O-RP*
    CA1 Interneuron Specific O-Targeting QuadD
    CA1 Oriens/Alveus
    CA1 Oriens-Bistratified
    CA1 Oriens-QuadA Projecting
    CA1 O-RPO*
    CA1 QuadD-RP*
    CA1 Quadrilaminar
    CA1 Interneuron Specific R-O
    CA1 R-Receiving Apical-Targeting
    CA1 R-RO*
    CA1 R-RP*
    CA1 Radiatum
    CA1 Interneuron Specific RO-O
    CA1 Interneuron Specific RO-R*
    CA1 RO-RP*
    CA1 RP-RPO*
    CA1 Schaffer Collateral-Associated
    CA1 Schaffer Collateral-Correlated*
    CA1 Schaffer Collateral-Receiving R-Targeting
    CA1 SO-SO
    CA1 SO-SO Projecting*
    CA1 Trilaminar
    CA1 Radial Trilaminar
    Sub CA1-Projecting Pyramidal
    EC LIII Small Pyramidal
    EC LIII Pyramidal

    Potential sources known to be avoided
    Excitatory or Inhibitory
    none known

    Targets of Output
    Known targets
    Excitatory or Inhibitory
    none known

    Potential targets
    Excitatory or Inhibitory
    CA1 Pyramidal
    CA1 Deep Pyramidal
    CA1 Superficial Pyramidal
    CA1 Radiatum Giant
    CA1 Axo-axonic
    CA1 Horizontal Axo-axonic
    CA1 Back-Projection
    CA1 Basket
    CA1 Horizontal Basket
    CA1 R-P Basket*
    CA1 Trilayer Basket*
    CA1 Vertical Basket*
    CA1 Basket CCK+
    CA1 Horizontal Basket CCK+*
    CA1 Trilayer Basket CCK+*
    CA1 Bistratified
    CA1 RO-receiving CA3-targeting*
    CA1 Hippocampo-subicular Projecting ENK+
    CA1 Ivy
    CA1 Interneuron Specific LMO-O
    CA1 LMR
    CA1 LMR-LM*
    CA1 Interneuron Specific LMR-O*
    CA1 LMR-R*
    CA1 Interneuron Specific LMR-R
    CA1 LMR Projecting
    CA1 O-LM
    CA1 Recurrent O-LM
    CA1 O-LMR
    CA1 Recurrent O-LMR*
    CA1 Interneuron Specific O-R
    CA1 O-RP*
    CA1 Interneuron Specific O-Targeting QuadD
    CA1 Oriens/Alveus
    CA1 Oriens-Bistratified
    CA1 Oriens-QuadA Projecting
    CA1 OR-LM
    CA1 O-RPO*
    CA1 Perforant Path-Associated
    CA1 Perforant Path-Associated QuadD
    CA1 QuadD-RP*
    CA1 Quadrilaminar
    CA1 Interneuron Specific R-O
    CA1 R-Receiving Apical-Targeting
    CA1 R-RO*
    CA1 R-RP*
    CA1 Radiatum
    CA1 Interneuron Specific RO-O
    CA1 Interneuron Specific RO-R*
    CA1 RO-RP*
    CA1 RP-RPO*
    CA1 Schaffer Collateral-Associated
    CA1 Schaffer Collateral-Correlated*
    CA1 Schaffer Collateral-Receiving R-Targeting
    CA1 SO-SO
    CA1 SO-SO Projecting*
    CA1 Trilaminar
    CA1 Radial Trilaminar

    Potential targets known to be avoided
    Excitatory or Inhibitory
    none known

    Oscillation Phase Locking
    Category
    Value