CA3 QuadD-LM
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
CA3 (i)12222 QuadD-LM S121402:O-LM Family:O-LM-like:CA3

Name derivation
This is a variant of the CA3 O-LM that has dendrites in four layers. CA3 distinguishes these cells from O-LM cells in other subregions.

Synonym(s)
CA3 CCK-expressing perforant path-associated cell
CA3 cell LM
CA3 O-LM cell
CA3 oriens lacunosum-moleculare associated cell
CA3 stratum lacunosum-moleculare 'selective' cell

List of articles
Click here to view the list
Amaral D  (2007) The Hippocampus Book
Hippocampal Neuroanatomy
Amaral D, Lavenex P.
The Hippocampus Book, 2007, Pages: 35 - 112
ISBN: 9780195100273
Tags: morphology, connectivity, synapse probabilities
Freund TF  (1996) Hippocampus
Interneurons of the hippocampus.
Freund TF, Buzsaki G.
Hippocampus, 1996, 6 (4), Pages: 347 - 470
PMID: 8915675; DOI: 10.1002/(SICI)1098-1063(1996)6:4<347::AID-HIPO1>3.0.CO;2-I
Tags: morphology, connectivity, synapse probabilities
Gulyas AI  (1993) Eur J Neurosci
Precision and variability in postsynaptic target selection of inhibitory cells in the hippocampal CA3 region.
Gulyas AI, Miles R, Hajos N, Freund TF.
Eur J Neurosci, 1993 Dec 1, 5 (12), Pages: 1729 - 1751
PMID: 8124523; DOI: 10.1111/j.1460-9568.1993.tb00240.x
Tags: morphology, connectivity, synapse probabilities
Lasztoczi B  (2011) J Neurosci
Terminal field and firing selectivity of cholecystokinin-expressing interneurons in the hippocampal CA3 area.
Lasztoczi B, Tukker JJ, Somogyi P, Klausberger T.
J Neurosci, 2011 Dec 7, 31 (49), Pages: 18073 - 18093
PMID: 22159120; DOI: 10.1523/JNEUROSCI.3573-11.2011
Tags: morphology, marker, phases


Morphology
Soma
CA3:SR
CA3:SL
CA3:SP
CA3:SO
Axons
CA3:SLM
Dendrites
CA3:SR
CA3:SL
CA3:SP
CA3:SO

Molecular markers
Positive
CB1 (confirmed by inference)
CCK (confirmed by inference)
Sub P Rec
Negative
CB
GABAa\alpha 6 (inference)
Gaba-a-alpha (inference)
mGluR1a (confirmed by inference)
NKB
NPY
PV (multiple confirming inferences)
SOM (confirmed by inference)
vGluT3
VIP
Mixed expression
None known

Electrophysiological properties
None known


Firing Pattern
Images
No image is associated with this neuron
Parameters
No parameter associated with this neuron
ModelDB Model
Model Accession Number PubMed ID

Sources of Input
Known sources
Excitatory or Inhibitory
none known

Potential sources
Excitatory or Inhibitory
DG Granule
DG Adult-Born Immature Granule*
DG Hilar Ectopic Granule
DG Semilunar Granule
DG HIPROM
CA3 Pyramidal
CA3 Athorny Pyramidal*
CA3c Pyramidal
CA3c Umbrella Pyramidal*
CA3 Giant
CA3 Granule
CA3 Basket
CA3 Basket CCK+
CA3 Horizontal Basket CCK+*
CA3 Mossy Fiber-Associated Basket CCK+*
CA3 Bistratified
CA3 Ivy
CA3 Bilayer Ivy*
CA3 LMR-Targeting
CA3 Lucidum*
CA3 Lucidum LAX
CA3 Lucidum ORAX
CA3 Lucidum-Radiatum
CA3 Spiny Lucidum
CA3 Mossy Fiber-Associated
CA3 Mossy Fiber-Associated ORDEN
CA3 O-LM
CA3 Interneuron Specific Oriens
CA3 Perforant Path-Associated Projecting*
CA3 Interneuron Specific Quad
CA3 Radiatum
CA3 SO-SO
CA3 Trilaminar
CA2 Pyramidal
CA2 Wide-Arbor Basket
CA1 Back-Projection
CA1 RO-receiving CA3-targeting*

Potential sources known to be avoided
Excitatory or Inhibitory
CA3 Axo-axonic
CA3 Horizontal Axo-axonic

Targets of Output
Known targets
Excitatory or Inhibitory
CA3 Pyramidal

Potential targets
Excitatory or Inhibitory
CA3 Athorny Pyramidal*
CA3c Umbrella Pyramidal*
CA3 Giant
CA3 Granule
CA3 Axo-axonic
CA3 Basket
CA3 Basket CCK+
CA3 LMR-Targeting
CA3 Perforant Path-Associated*
CA3 Perforant Path-Associated Projecting*

Potential targets known to be avoided
Excitatory or Inhibitory
none known

Oscillation Phase Locking
Category
Value
Theta (deg):-165.00
Theta range:[-165.00, -165.00]
Theta measurements:1
Theta representative selection:   rats, adult, male,
juxtacellular, urethane plus supplemental doses of ketamine and xylazine
SWR ratio:2.66
SWR ratio range:[2.66, 2.66]
SWR ratio measurements:1
SWR ratio representative selection:   rats, adult, male,
juxtacellular, urethane plus supplemental doses of ketamine and xylazine
In vivo firing rate (Hz):6.14
Firing rate range:[6.14, 6.14]
Firing rate measurements:1
Firing rate representative selection:   rats, adult, male,
juxtacellular, urethane plus supplemental doses of ketamine and xylazine
Other:firingRateNonBaseline
Other representative selection:   rats, adult, male,
juxtacellular, urethane plus supplemental doses of ketamine and xylazine