CA3 Lucidum ORAX
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
CA3 (i)03311 Lucidum ORAX S131502:Collateral-related:RO-targeting:CA3

Name derivation
This name uses the common core of all of the names in the cited literature. The modifier describes the "ORiens AXons" that distinguish this from the other lucidum cell types.

Synonym(s)
CA3 aspiny neuron in stratum lucidum
CA3 aspiny neuron with cell body in stratum lucidum
CA3 aspiny stratum lucidum cell
CA3 spiny neuron in stratum lucidum
CA3 spiny stratum lucidum neuron

List of articles
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Spruston N  (1997) J Comp Neurol
Interneurons in the stratum lucidum of the rat hippocampus: an anatomical and electrophysiological characterization.
Spruston N, Lubke J, Frotscher M.
J Comp Neurol, 1997 Sep 1, 385 (3), Pages: 427 - 440
PMID: 9300769; DOI: 10.1002/(SICI)1096-9861(19970901)385:3<427::AID-CNE7>3.0.CO;2-5
Tags: morphology, membrane biophysics, connectivity, firing patterns, synapse probabilities


Morphology
Soma
CA3:SL
Axons
CA3:SR
CA3:SL
CA3:SP
CA3:SO
Dendrites
CA3:SR
CA3:SL

Representative figure
Interneurons in the stratum lucidum of the rat hippocampus: an anatomical and electrophysiological characterization.
Spruston N, Lubke J, Frotscher M
J Comp Neurol, 1997 Sep 1, 385 (3), pages: 427 - 440
PMID: 9300769; DOI: 10.1002/(SICI)1096-9861(19970901)385:3<427::AID-CNE7>3.0.CO;2-5


"Fig. 1. A, B: Dendritic trees and axonal arborizations of two [CA3] spiny neurons in stratum lucidum {CA3 Lucidum ORAX} {CA3 Lucidum-Radiatum}, intracellularly filled with biocytin."


Molecular markers
Positive
None known
Negative
GABAa\alpha 6 (inference)
Mixed expression
None known

Electrophysiological properties
Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max]

Resting membrane potential (Vrest): -61±6.0 mV (9); 2 sources (17): [-61 , -59]
Input resistance (Rin): 284±180.0 MΩ (9); 2 sources (17): [284 , 341]
Time constant (τm): 42±17.0 ms (8); 2 sources (15): [28 , 42]
Threshold potential (Vthresh): 19.2 mV (1); 2 sources (2): [16.3 , 19.2]
Fast afterhyperpolaziring potential amplitude (Fast AHP): 15±6.6 mV (9); 2 sources (17): [15 , 15.1]
Action potential amplitude (APampl): 68.3 mV (1); 2 sources (2): [68.3 , 77.7]
Action potential width (APwidth): 0.53±0.2 ms (9); 2 sources (17): [0.53 , 0.8]
Max firing rate (Max F.R.): 75±28.3 Hz (8); 2 sources (17): [75 , 115]
Slow afterhyperpolarizing potential amplitude (Slow AHP): 6.6±3.9 mV (9); 2 sources (17): [4.6 , 6.6]
Sag ratio: 0.81±0.1 (8); 2 sources (16): [0.81 , 0.9]

Notes
The 03331 and 03301 classes have been mapped into this 03311 class, since they differ only by axons and dendrites in SP. Borderline dendrites in SP

Firing Pattern
Images
Image MissingImage MissingImage MissingImage Missing
Parameters View page
ASP. [Evidence] [Firing Pattern]
D.NASP [Evidence] [Firing Pattern]
NASP [Evidence] [Firing Pattern]
PSTUT [Evidence] [Firing Pattern]

Izhikevich Model
Parameters Single Compartment Downloads Simulate
subtype: 1 k=1.03;a= 0.042;b= -5.07;d= 68;C= 67;Vr= -60.02;Vt= -47.97;Vpeak= 11.09;Vmin= -59.38; Simulate
subtype: 2 k=1.2;a= 0;b= 2.04;d= 5;C= 262;Vr= -61.03;Vt= -47.1;Vpeak= 9.97;Vmin= -51.67; Simulate
Images
Image MissingImage Missing
ModelDB Model
Model Accession Number PubMed ID

Sources of Input
Known sources
Excitatory or Inhibitory
none known

Potential sources
Excitatory or Inhibitory
DG Granule
DG Adult-Born Immature Granule*
DG Hilar Ectopic Granule
DG Semilunar Granule
DG HIPROM
CA3 Pyramidal
CA3c Pyramidal
CA3c Umbrella Pyramidal*
CA3 Granule
CA3 Mossy Fiber-Associated Basket CCK+*
CA3 Bistratified
CA3 Ivy
CA3 Bilayer Ivy*
CA3 LMR-Targeting
CA3 Lucidum*
CA3 Lucidum LAX
CA3 Lucidum ORAX
CA3 Lucidum-Radiatum
CA3 Spiny Lucidum
CA3 Mossy Fiber-Associated
CA3 Mossy Fiber-Associated ORDEN
CA3 O-LM
CA3 Interneuron Specific Oriens
CA3 Perforant Path-Associated Projecting*
CA3 Interneuron Specific Quad
CA3 Radiatum
CA3 Trilaminar
CA2 Pyramidal
CA1 Back-Projection

Potential sources known to be avoided
Excitatory or Inhibitory
none known

Targets of Output
Known targets
Excitatory or Inhibitory
none known

Potential targets
Excitatory or Inhibitory
CA3 Pyramidal
CA3 Athorny Pyramidal*
CA3c Pyramidal
CA3c Umbrella Pyramidal*
CA3 Giant
CA3 Granule
CA3 Axo-axonic
CA3 Horizontal Axo-axonic
CA3 Basket
CA3 Basket CCK+
CA3 Horizontal Basket CCK+*
CA3 Mossy Fiber-Associated Basket CCK+*
CA3 Bistratified
CA3 Ivy
CA3 Bilayer Ivy*
CA3 LMR-Targeting
CA3 Lucidum*
CA3 Lucidum LAX
CA3 Lucidum ORAX
CA3 Lucidum-Radiatum
CA3 Spiny Lucidum
CA3 Mossy Fiber-Associated
CA3 Mossy Fiber-Associated ORDEN
CA3 O-LM
CA3 Recurrent O-LM*
CA3 Interneuron Specific Oriens
CA3 Perforant Path-Associated*
CA3 Perforant Path-Associated Projecting*
CA3 Interneuron Specific Quad
CA3 QuadD-LM
CA3 Radiatum
CA3 R-LM
CA3 SO-SO
CA3 Trilaminar
CA2 Wide-Arbor Basket

Potential targets known to be avoided
Excitatory or Inhibitory
none known

Oscillation Phase Locking
Category
Value