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DG (i)2322 Interneuron-Specific Inner MOlecular layer-Targeting (IS IMOT) cells [1106]
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Related types:
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DG (i)2322 HICAP (v1.0 active)
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Notes: These cells are VIP+ and are speculated by the authors to be interneuron specific, which distinguishes them from the active type, which are inferred to be CR- and VIP-.
VIP+. Ephys. FP. Lengths.
After review of DG (i) 2322 IS HICAP (#1106), I am in agreement with the evidence as presented in the provided packet and approve this type for v2.0. - JDK 11/22/2021
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I approve the new type, but I'm not convinced by the name. I don't think we should adopt the same name (except for the IS part) for IS and non-IS neurons, as this can create unneeded confusion (I'm already regretting "IS LM-R" vs "LMR" in CA1, but at least we have an extra hyphen there). Perhaps we could consider something like IS-IMOT (inner molecular targeting), but I'm also open to other proposals. - GAA 01/25/2022
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The authors refer to the cells as molecular layer-projecting (MP) cells. Perhaps we could amend that into Interneuron Specific Inner MOlecular layer-Projecting (IS IMOP) cells? - DWW 01/28/2022
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I am in agreement with GAA's comments and favor changing the name to either IS IMOT or IS IMOP. As far as choosing between  the two, I am in favor of IMOT despite the author's referral to these cell as molecular layer-projecting. My rationale is that we have used the "projecting" nomenclature so far to denote axonal presence for a neuron type outside of the layer its somata have been found, and the "targeting" nomenclature for within the same layer. Therefore, I think that IMOT is a better choice for describing this new neuron type. - JDK 01/28/2022
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That logic makes sense. I am in agreement with your suggestion for IS IMOT. - DWW 01/28/2022
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