MEC LI Neurogliaform*
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
MEC (i)300000 LI Neurogliaform* S152306:GABAergic:iLI-II:EC

Name derivation
This is the cited name.

Synonym(s)

List of articles
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Szocs S  (2022) Frontiers in Neuroanatomy
Neurogliaform cells mediate feedback inhibition in the medial entorhinal cortex
Szocs S, Henn-Mike N, Agocs-Laboda A, Szabo-Meleg E, Varga C.
Frontiers in Neuroanatomy, 2022, 16, Pages: 779390 -
PMID: 36003850; DOI: 10.3389/fnana.2022.779390
Tags: morphology, marker, membrane biophysics


Morphology
Soma
EC:I
Axons
EC:I
Dendrites
EC:I

Representative figure
Neurogliaform cells mediate feedback inhibition in the medial entorhinal cortex
Szocs S, Henn-Mike N, Agocs-Laboda A, Szabo-Meleg E, Varga C
Frontiers in Neuroanatomy, 2022, 16 pages: 779390 -
PMID: 36003850; DOI: 10.3389/fnana.2022.779390


"FIGURE 4 The distribution of neurogliaform cells does not correlate with dendritic clustering of layer II pyramidal cells. Neurolucida partial reconstruction of two paired recordings. (A) Neurogliaform cell (soma and dendrites blue, axons red) together with layer II pyramidal cell (soma and dendrites, black). ... (scale bar: 50 [micro]m)."


Molecular markers
Positive
alpha-actinin-2
RLN
Negative
GABAa\alpha 6 (inference)
PV (multiple confirming inferences)
Mixed expression
None known

Electrophysiological properties
Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max]

Resting membrane potential (Vrest): -65.1±0.5 mV (34); 1 source
Time constant (τm): 7.5±0.4 ms (34); 1 source

Notes

MEC (i)300000 LI Neurogliaform cells (MEC LI NGF) [6129]

Related types: CEC (i)230000 LII Basket-Neurogliaform (v1.0 active)

Notes: This neuron type is restricted entirely to MEC LI, which distinguishes it from the other hybrid type.

N = 2.

Ephys. FP. Markers. Synaptic parameters. Counts.

Slam dunk yes. - DWW 05/12/2023

I concur it is a slam dunk yes, especially with the accompanying information provided for the counts, ephys, markers, and synaptic parameters. - JDK 05/12/2023

approved - GAA 05/22/2023

Firing Pattern
Images
No image is associated with this neuron
Parameters
No parameter associated with this neuron
ModelDB Model
Model Accession Number PubMed ID

Sources of Input
Known sources
Excitatory or Inhibitory
none known

Potential sources
Excitatory or Inhibitory
EC LI-II Pyramidal-Fan
MEC LII Stellate
EC LII-III Pyramidal-Tripolar
LEC LIII Multipolar Principal
MEC LIII Complex Pyramidal
MEC LIII Bipolar Complex Pyramidal
MEC LV Pyramidal
MEC LI-II Polar Interneuron*
MEC LIII Multipolar Interneuron
MEC LI Neurogliaform*
EC LII-III Superficial Polymorphic Interneuron*
MEC LIII Superficial Trilayered Interneuron

Potential sources known to be avoided
Excitatory or Inhibitory
none known

Targets of Output
Known targets
Excitatory or Inhibitory
none known

Potential targets
Excitatory or Inhibitory
EC LI-II Multipolar-Pyramidal
EC LI-II Pyramidal-Fan
MEC LII Oblique Pyramidal
MEC LII Stellate
MEC LII-III Pyramidal-Multiform
EC LII-III Pyramidal-Tripolar
EC LIII Small Pyramidal
LEC LIII Complex Pyramidal
MEC LIII Complex Pyramidal
EC LIII Pyramidal
EC LIII Stellate
EC LIII-V Bipolar Pyramidal
EC LIV-V Pyramidal-Horizontal
MEC LV Principal*
MEC LV Pyramidal
EC LV Deep Pyramidal
MEC LV Superficial Pyramidal
EC LII Basket-Neurogliaform
EC LIII Bipolar Interneuron*
MEC LIII Superficial Multipolar Interneuron
MEC LI Neurogliaform*
EC LII-III Superficial Polymorphic Interneuron*
MEC LIII Superficial Trilayered Interneuron

Potential targets known to be avoided
Excitatory or Inhibitory
none known

Oscillation Phase Locking
Category
Value