Sub Wide-arbor Polymorphic*
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
Sub (i)023 Wide-arbor Polymorphic* S131505:Collateral-related:RO-targeting:CA1

Name derivation
This name is derived from the cells' general physical description. Sub distinguishes these cells from pyramidal cells in other subregions.

Synonym(s)
Sub Chrna2 cell

List of articles
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Nichol H  (2018) Frontiers in Cellular Neuroscience
Electrophysiological and morphological characterization of chrna2 cells in the subiculum and CA1 of the hippocampus: an optogenetic investigation
Nichol H, Amilhon B, Manseau F, Badrinarayanan S, Williams S.
Frontiers in Cellular Neuroscience, 2018, 12, Pages: 32 -
PMID: 29487503; DOI: 10.3389/fncel.2018.00032
Tags: morphology, marker, membrane biophysics


Morphology
Soma
SUB:SP
SUB:PL
Axons
SUB:PL
Dendrites
SUB:SP
SUB:PL

Molecular markers
Positive
Chrna2
SOM
Negative
5HT-3 (inference)
ErbB4 (multiple confirming inferences)
GABAa\alpha 6 (inference)
Mixed expression
None known

Electrophysiological properties
Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max]

Resting membrane potential (Vrest): -49.9±1.5 mV (1); 1 source
Input resistance (Rin): 387.8±47.2 MΩ (1); 1 source
Action potential amplitude (APampl): 91.8±1.4 mV (1); 1 source
Action potential width (APwidth): 1.5±0.1 ms (1); 1 source
Max firing rate (Max F.R.): 26±2.1 Hz (1); 1 source

Notes

Sub (i)023 Wide-arbor Polymorphic (wPo) cells [5012]

Related types: Sub (i)133 Recurrent Polymorphic-Moleculare

Notes:

FP present. Chrna2+. SOM+. Ephys present.

p6 -> The slicing orientation was unusual to me. I am unable to judge without layers being marked.

Four cells had axons in SUB:SM. Will they be SUB:113 type? - KM 05/24/2018

I agree it is a little difficult to interpret given the minimal layer lines provided; however, I am willing to be on the generous side given the scarcity of neuron types we have in the subiculum. - DWW 06/05/2018

The interpretation of the axons and dendrites had been accidentally reversed in the previous iteration of this packet. There is now also a second packet that reflects the extension of the axons into Sub:SM. - 06/05/2018

OK. However, the presence of Dendrites in SM is fuzzy. I am not so happy about these packets. I was thinking. Is it possible to contact the authors to get all 8 reconstructions or anything they are ready to share. - KM 06/09/2018

OK. tentatively approve both [Sub Chrna2] packets. - GAA 07/18/2018

Firing Pattern
Images
No image is associated with this neuron
Parameters
No parameter associated with this neuron
ModelDB Model
Model Accession Number PubMed ID

Sources of Input
Known sources
Excitatory or Inhibitory
none known

Potential sources
Excitatory or Inhibitory
CA3 Trilaminar
CA1 Pyramidal
CA1 Deep Pyramidal
CA1 Superficial Pyramidal
CA1 Hippocampo-subicular Projecting ENK+
CA1 Oriens-QuadA Projecting
CA1 SO-SO Projecting*
CA1 Trilaminar
Sub CA1-Projecting Pyramidal
Sub EC-Projecting Pyramidal
Sub Pyramidale Multipolar Interneuron*
Sub Wide-arbor Polymorphic*
Sub Recurrent Polymorphic-Moleculare*
EC LI-II Pyramidal-Fan
MEC LII Stellate
EC LII-III Pyramidal-Tripolar
EC LIV-VI Deep Multipolar Principal
MEC LV Pyramidal

Potential sources known to be avoided
Excitatory or Inhibitory
Sub Axo-axonic

Targets of Output
Known targets
Excitatory or Inhibitory
none known

Potential targets
Excitatory or Inhibitory
Sub Wide-arbor Polymorphic*
Sub Recurrent Polymorphic-Moleculare*

Potential targets known to be avoided
Excitatory or Inhibitory
none known

Oscillation Phase Locking
Category
Value