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| Morphology |
| Soma | |
| CA2:SP |
| Axons | |
| CA2:SR |
| Dendrites | |
| CA2:SR | |
| CA2:SO |
| Representative figure |
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SP-SR interneurones: a novel class of neurones of the CA2 region of the hippocampus. Mercer A, Botcher NA, Eastlake K, Thomson AM Hippocampus, 2012 Aug, 22 (8), pages: 1758 - 1769 PMID: 22431345; DOI: 10.1002/hipo.22010 |
 "FIGURE 1. Morphological features of SP-SR interneurones of the CA2 region of the hippocampus. SO, stratum oriens; SP, stratum pyramidale; SR, stratum radiatum; SLM, stratum lacunosum- moleculare; PV, parvalbumin; CCK, cholecystokinin. (A-C) Reconstructions of three SP-SR interneurones [C] {CA2 SP-SR} (dendrites in black and axon in red). The broad dendritic arbors of these interneurones extended radially through SO and SR but did not enter SLM. Their axons arborized mainly in SR of the CA2 region with only a few branches, if any, extending to SO, SP, or SLM. The majority of these axons were restricted to subregions of SR of the CA2 region, with some branches extending into proximal CA1 or CA3. The SP-SR interneurones were PV- and CCK-immunonegative." |
| Molecular markers |
| Positive | |
| None known |
| Negative | |
| CCK | |
| GABAa\alpha 6 (inference) | |
| PV |
| Mixed expression | |
| None known |
| Electrophysiological properties |
| Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max] | |
| Resting membrane potential (Vrest): -71±4.5 mV (8); 1 source | |
| Input resistance (Rin): 82.6±24.4 MΩ (8); 1 source | |
| Time constant (τm): 12.7±3.8 ms (8); 1 source | |
| Threshold potential (Vthresh): 19 mV (1); 1 source | |
| Fast afterhyperpolaziring potential amplitude (Fast AHP): 11.5 mV (1); 1 source | |
| Action potential amplitude (APampl): 67 mV (1); 1 source | |
| Action potential width (APwidth): 0.5±0.1 ms (8); 1 source | |
| Max firing rate (Max F.R.): >160 Hz (1); 1 source | |
| Slow afterhyperpolarizing potential amplitude (Slow AHP): 3.3 mV (1); 1 source | |
| Sag ratio: 0.86 (1); 1 source |
| Notes |
|
CA2 (i)0302 SP-SR cells [3008]
Notes: Neurite differences in the principal cell Layers invoked rule: when compressing types, leave axons in the PCL because of the issue of target specificity, but discount dendrites. Because of the invoked rule, the 0332 type should remain unchanged, but the 0322 type should be merged with the 0302 type as 0302. - DWW 10/19/2021
Update: Principal cell layer invoked rule: record axons in the PCL when boutons are present or when axons are branching and ostensibly targeting the PCL and not just passing through, but discount dendrites. - 11/15/2021 After re-review with our updated new invoked rule, I am still in favor of compression for the 0322 and 0302 reconstructions to be considered as 0302, with 0332 remaining unchanged. - JDK 11/22/2021
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| Firing Pattern |
| Images | |
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| Parameters | View page | |
| TSTUT. | [Evidence] [Firing Pattern] | |
| TSTUT.SLN | [Evidence] [Firing Pattern] |
| Izhikevich Model |
| Parameters | Single Compartment | Downloads | Simulate |
| subtype: 1 k=3.59;a= 0.003;b= 48.43;d= 64;C= 226;Vr= -71.92;Vt= -57.05;Vpeak= -6.5;Vmin= -66.94; | Simulate |
| Images | |
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| ModelDB Model |
| Model Accession Number | PubMed ID |
| Sources of Input |
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| Targets of Output |
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| Oscillation Phase Locking |
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