DG Basket
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
DG (i)2232 Basket S110701:Perisomatic-targeting:Basket:DG

Name derivation
This name omits any descriptive adjectives because not all of the subtypes are clearly known to be PV+. DG distinguishes these cells from basket cells in other subregions.

Synonym(s)
DG basket 1 cell
DG basket cell
DG basket-cell
DG FS PV positive basket cell
DG fusiform basket cell
DG GCL cell
DG HICAP-like cell
DG HICAP-like interneuron
DG hilar basket cell
DG hilar region basket cell
DG horizontal basket cell
DG IML cell
DG interneuron with axonal arbors concentrated in the granule cell layer
DG interneuron with inner molecular layer axons
DG inverted fusiform basket cell
DG molecular layer basket cell
DG PV-BC
DG PV+ BC
DG pyramidal basket cell

List of articles
Click here to view the list
Amaral D  (2007) The Hippocampus Book
Hippocampal Neuroanatomy
Amaral D, Lavenex P.
The Hippocampus Book, 2007, Pages: 35 - 112
ISBN: 9780195100273
Tags: morphology, connectivity, synapse probabilities
Amaral DG  (2007) Prog Brain Res
The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies).
Amaral DG, Scharfman HE, Lavenex P.
Prog Brain Res, 2007, 163, Pages: 3 - 22
PMID: 17765709; DOI: 10.1016/S0079-6123(07)63001-5
Tags: morphology, connectivity, synapse probabilities
Bartos M  (2001) J Neurosci
Rapid signaling at inhibitory synapses in a dentate gyrus interneuron network.
Bartos M, Vida I, Frotscher M, Geiger JR, Jonas P.
J Neurosci, 2001 Apr 15, 21 (8), Pages: 2687 - 2698
PMID: 11306622
Tags: morphology, connectivity, synapse probabilities
Bartos M  (2010) Hippocampal Microcircuits: A Computational Modeler's Resource Book
Fast and Slow GABAergic Transmission in Hippocampal Circuits
Bartos M, Sauer JF, Vida I, Kulik A.
Hippocampal Microcircuits: A Computational Modeler's Resource Book, 2010, Pages: 129 - 162
ISBN: 9781441909954
Tags: morphology, connectivity, synapse probabilities
Dyhrfjeld-Johnsen J  (2007) J Neurophysiol
Topological determinants of epileptogenesis in large-scale structural and functional models of the dentate gyrus derived from experimental data.
Dyhrfjeld-Johnsen J, Santhakumar V, Morgan RJ, Huerta R, Tsimring L, Soltesz I.
J Neurophysiol, 2007 Feb, 97 (2), Pages: 1566 - 1587
PMID: 17093119; DOI: 10.1152/jn.00950.2006
Tags: morphology, connectivity, synapse probabilities
Freund TF  (1996) Hippocampus
Interneurons of the hippocampus.
Freund TF, Buzsaki G.
Hippocampus, 1996, 6 (4), Pages: 347 - 470
PMID: 8915675; DOI: 10.1002/(SICI)1098-1063(1996)6:4<347::AID-HIPO1>3.0.CO;2-I
Tags: morphology, marker, connectivity, synapse probabilities
Han ZS  (1993) Eur J Neurosci
A high degree of spatial selectivity in the axonal and dendritic domains of physiologically identified local-circuit neurons in the dentate gyrus of the rat hippocampus.
Han ZS, Buhl EH, Lorinczi Z, Somogyi P.
Eur J Neurosci, 1993 May 1, 5 (5), Pages: 395 - 410
PMID: 8261117; DOI: 10.1111/j.1460-9568.1993.tb00507.x
Tags: morphology, connectivity, synapse probabilities
Hosp JA  (2014) Hippocampus
Morpho-physiological criteria divide dentate gyrus interneurons into classes.
Hosp JA, Struber M, Yanagawa Y, Obata K, Vida I, Jonas P, Bartos M.
Hippocampus, 2014 Feb, 24 (2), Pages: 189 - 203
PMID: 24108530; DOI: 10.1002/hipo.22214
Tags: synapse probabilities
Houser CR  (2007) Prog Brain Res
Interneurons of the dentate gyrus: an overview of cell types, terminal fields and neurochemical identity.
Houser CR.
Prog Brain Res, 2007, 163, Pages: 217 - 232
PMID: 17765721; DOI: 10.1016/S0079-6123(07)63013-1
Tags: morphology, marker, connectivity, synapse probabilities
Morgan RJ  (2007) Prog Brain Res
Modeling the dentate gyrus.
Morgan RJ, Santhakumar V, Soltesz I.
Prog Brain Res, 2007, 163, Pages: 639 - 658
PMID: 17765743; DOI: 10.1016/S0079-6123(07)63035-0
Tags: morphology, connectivity, synapse probabilities
Morgan RJ  (2010) Hippocampal Microcircuits: A Computational Modeler's Resource Book
Microcircuit Model of the Dentate Gyrus in Epilepsy
Morgan RJ, Soltesz I.
Hippocampal Microcircuits: A Computational Modeler's Resource Book, 2010, Pages: 495 - 526
ISBN: 9781441909954
Tags: morphology, connectivity, synapse probabilities
Mott DD  (1997) J Neurosci
Interneurons of the dentate-hilus border of the rat dentate gyrus: morphological and electrophysiological heterogeneity.
Mott DD, Turner DA, Okazaki MM, Lewis DV.
J Neurosci, 1997 Jun 1, 17 (11), Pages: 3990 - 4005
PMID: 9151716
Tags: morphology, synapse probabilities
Patton PE  (1995) Hippocampus
Connection matrix of the hippocampal formation: I. The dentate gyrus.
Patton PE, McNaughton B.
Hippocampus, 1995, 5 (4), Pages: 245 - 286
PMID: 8589792; DOI: 10.1002/hipo.450050402
Tags: morphology, marker, connectivity, synapse probabilities
Ribak CE  (1983) J Neurocytol
Five types of basket cell in the hippocampal dentate gyrus: a combined Golgi and electron microscopic study.
Ribak CE, Seress L.
J Neurocytol, 1983 Aug, 12 (4), Pages: 577 - 597
PMID: 6619905; DOI: 10.1007/BF01181525
Tags: morphology, connectivity, synapse probabilities
Ribak CE  (2007) Prog Brain Res
Ultrastructure and synaptic connectivity of cell types in the adult rat dentate gyrus.
Ribak CE, Shapiro LA.
Prog Brain Res, 2007, 163, Pages: 155 - 166
PMID: 17765717; DOI: 10.1016/S0079-6123(07)63009-X
Tags: morphology, connectivity, synapse probabilities
Santhakumar V  (2008) Computational neuroscience in epilepsy
Modeling circuit alterations in epilepsy: A focus on mossy cell loss and mossy fiber sprouting in the dentate gyrus
Santhakumar V.
Computational neuroscience in epilepsy, 2008, Pages: 89 - 111
ISBN: 9780123736499
Tags: morphology, connectivity, synapse probabilities
Sik A  (1997) Eur J Neurosci
Interneurons in the hippocampal dentate gyrus: an in vivo intracellular study.
Sik A, Penttonen M, Buzsaki G.
Eur J Neurosci, 1997 Mar, 9 (3), Pages: 573 - 588
PMID: 9104599; DOI: 10.1111/j.1460-9568.1997.tb01634.x
Tags: morphology, marker, membrane biophysics, connectivity, synapse probabilities
Spruston N  (2007) The Hippocampus Book
Chapter 5: Structural and functional properties of hippocampal neurons
Spruston N, McBain C.
The Hippocampus Book, 2007, Pages: 133 - 200
ISBN: 9780195100273
Tags: morphology, connectivity, synapse probabilities
Struble RG  (1978) Brain Res
Anatomical evidence for interlamellar inhibition in the fascia dentata.
Struble RG, Desmond NL, Levy WB.
Brain Res, 1978 Sep 8, 152 (3), Pages: 580 - 585
PMID: 687975; DOI: 10.1016/0006-8993(78)91113-7
Tags: morphology
Szabo GG  (2017) Cell Reports
Extended Interneuronal Network of the Dentate Gyrus
Szabo GG, Du X, Oijala M, Varga C, Parent JM, Soltesz I.
Cell Reports, 2017, 20 (6), Pages: 1262 - 1268
PMID: 28793251; DOI: 10.1016/j.celrep.2017.07.042
Tags: phases
Vida I  (2010) Hippocampal Microcircuits: A Computational Modeler's Resource Book
Morphology of Hippocampal Neurons
Vida I.
Hippocampal Microcircuits: A Computational Modeler's Resource Book, 2010, Pages: 27 - 68
ISBN: 9781441909954
Tags: morphology, connectivity, synapse probabilities

Supplemental PMIDs

List of Hippocampome.org to NeuroMorpho.Org mappings
Click here to view the list of mappings
  • Bartos
  • Jonas
    • BC1 (fits the general description of "DG Basket" based on the distribution of axons and dendrites)
    • BC2 (Fig S1A)
    • BC4 (fits the general description of "DG Basket" based on the distribution of axons and dendrites)
    • more ...
  • Lien
  • McBain
    • 2010-01-15-6 (fits the general description of "DG Basket" based on the distribution of axons and dendrites)
  • Santhakumar
  • Schwaller
  • Turner
  • Vida
  • Wadiche

    • Morphology
    Soma
    DG:SG
    Axons
    DG:SG
    Dendrites
    DG:SMo
    DG:SMi
    DG:SG
    DG:H

    Representative figure
    Rapid signaling at inhibitory synapses in a dentate gyrus interneuron network.
    Bartos M, Vida I, Frotscher M, Geiger JR, Jonas P
    J Neurosci, 2001 Apr 15, 21 (8), pages: 2687 - 2698
    PMID: 11306622;


    "Figure 3. Camera lucida reconstruction of a synaptically connected BC[basket cell]-BC pair {DG Basket} [in the dentate gyrus]. Soma and dendrites of the presynaptic BC are drawn in green. Axonal arborization of the presynaptic BC is drawn in red. Soma and dendrites of the postsynaptic BC are drawn in black. Axonal arborization of the postsynaptic BC is drawn in blue. Only the portions of the axons that could be unequivocally traced back to the soma are depicted. Synaptic contacts (confirmed by subsequent electron microscopy; see Fig. 4) are indicated by arrowheads. Additionally, the postsynaptic BC showed three autaptic contacts (confirmed by electron microscopy; data not shown). Note that the axonal arborization of both BCs was largely confined to the [dentate gyrus] granule cell layer, identifying them as BCs. ml, Molecular layer; gcl, granule cell layer."


    Molecular markers
    Positive
    Gaba-a-alpha (inference)
    PV
    Negative
    5HT-3 (inference)
    AR-beta1 (inference)
    AR-beta2 (inference)
    CB (multiple confirming inferences)
    CB1 (multiple confirming inferences)
    CCK (confirmed by inference)
    CGRP (inference)
    CR (multiple confirming inferences)
    GABAa\alpha 6 (inference)
    mGluR1a (inference)
    SOM (multiple confirming inferences)
    vGluT3 (inference)
    VIP (confirmed by inference)
    Mixed expression
    None known

    Electrophysiological properties
    Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max]

    Input resistance (Rin): 43±5 MΩ (3); 2 sources (15): [43 , 90.1]
    Action potential width (APwidth): 0.25±0.04 ms (3); 2 sources (15): [0.25 , 0.6]
    Max firing rate (Max F.R.): 230±15 Hz (3); 2 sources (15): [145.3 , 230]
    Threshold potential (Vthresh): [17.6, 19.0] mV (2); 2 sources (3): [12 , 17.6]
    Fast afterhyperpolaziring potential amplitude (Fast AHP): 20±2.3 mV (3); 2 sources (4): [11 , 20]
    Action potential amplitude (APampl): [71.6, 73.6] mV (2); 2 sources (3): [42 , 71.6]
    Sag ratio: 0.97±0.02 (3); 2 sources (4): [0.92 , 0.97]
    Resting membrane potential (Vrest): -62±3 mV (3); 1 source
    Time constant (τm): 10±1 ms (3); 1 source
    Slow afterhyperpolarizing potential amplitude (Slow AHP): 2.3±0.2 mV (3); 1 source

    Notes
    Contact proximal dendritic shafts of apical dendrites and somata of interneurons and GCs. Perisomatic targeting interpreted as SG. Extended interpretation of SG in apical and basal directions.

    Firing Pattern
    Images
    Image MissingImage Missing
    Parameters View page
    NASP [Evidence] [Firing Pattern]

    Izhikevich Model
    Parameters Single Compartment Downloads Simulate
    subtype: 1 k=0.81;a= 0.097;b= 1.89;d= 553;C= 208;Vr= -61.02;Vt= -37.84;Vpeak= 14.08;Vmin= -36.23; Simulate
    subtype: 2 k=0.55;a= 0.043;b= -3.15;d= 231;C= 132;Vr= -62.16;Vt= -31.39;Vpeak= 13.2;Vmin= -37.71; Simulate
    Images
    Image MissingImage Missing
    ModelDB Model
    Model Accession Number PubMed ID
    124513 15342722
    124513 17093119
    124513 18375756
    124513 17765743
    206372 27784124
    51781 15342722
    155568 24811867
    155568 22811762
    185355 25269417
    140789 20080772
    229750 28970502
    206397 28132825
    124513 15342722
    124513 17093119
    124513 18375756
    124513 17765743
    206372 27784124
    51781 15342722
    155568 24811867
    155568 22811762
    185355 25269417
    140789 20080772
    229750 28970502
    206397 28132825

    Sources of Input
    Known sources
    Excitatory or Inhibitory
    DG Granule
    DG Basket
    DG Basket CCK+
    DG HICAP
    DG HIPP

    Potential sources
    Excitatory or Inhibitory
    DG Adult-Born Immature Granule*
    DG Hilar Ectopic Granule
    DG Semilunar Granule
    DG Cajal-Retzius*
    DG Local-Projecting Cajal-Retzius*
    DG Mossy
    DG Mossy MOLDEN
    DG AIPRIM
    DG Granulosum-targeting Axo-axonic*
    DG Basket GRALDEN*
    DG Interneuron Specific COLTAR*
    DG COM-MOPP*
    DG Interneuron Specific IMOT*
    DG Hilus-Associated Interneuron*
    DG Interneuron Specific HIMOLD*
    DG Recurrent HIPP*
    DG HIPP-CAP*
    DG Recurrent HIPP-CAP*
    DG Interneuron Specific HIPRO*
    DG HIPROM
    DG Ivy*
    DG MOCAP
    DG MOLAX
    DG Molecular Layer*
    DG Outer Molecular Layer
    DG Total Molecular Layer
    DG MOPP
    DG Neurogliaform
    DG Wide-Arbor Neurogliaform*
    CA3c Pyramidal
    CA3c Umbrella Pyramidal*
    CA3 Spiny Lucidum
    CA3 Mossy Fiber-Associated
    CA3 Mossy Fiber-Associated ORDEN
    CA3 Perforant Path-Associated Projecting*
    CA3 Interneuron Specific Quad
    CA2 Pyramidal
    CA1 Local-Projecting Cajal-Retzius*
    CA1 Back-Projection
    CA1 LMR Projecting
    CA1 Neurogliaform Projecting
    CA1 Perforant Path-Associated
    EC LI-II Pyramidal-Fan
    MEC LII Stellate
    EC LII-III Pyramidal-Tripolar
    EC LIV-V Pyramidal-Horizontal
    MEC LV Pyramidal

    Potential sources known to be avoided
    Excitatory or Inhibitory
    DG Axo-axonic
    DG Axo-axonic GRALDEN*

    Targets of Output
    Known targets
    Excitatory or Inhibitory
    DG Granule
    DG Basket
    DG Basket CCK+
    DG HICAP

    Potential targets
    Excitatory or Inhibitory
    DG Mossy MOLDEN
    DG AIPRIM
    DG Axo-axonic
    DG Granulosum-targeting Axo-axonic*
    DG Interneuron Specific IMOT*
    DG HIPROM
    DG Ivy*
    DG MOCAP
    DG Outer Molecular Layer

    Potential targets known to be avoided
    Excitatory or Inhibitory
    none known

    Oscillation Phase Locking
    Category
    Value
    SWR ratio:2.22
    SWR ratio range:[2.22, 2.22]
    SWR ratio measurements:1
    SWR ratio representative selection:   mice, adult, male,
    juxtacellular, freely moving
    Other:DS_ratio
    Other representative selection:   mice, adult, male,
    juxtacellular, freely moving