DG HIPROM
* indicates new v2.0 neuron type
Name Supertype (ID:Family:Type:Subregion)
DG (i)1333p-CA3_01111 HIPROM S121001:O-LM Family:HIPP-like:DG

Name derivation
This is a new name derived from the cited descriptor in the vein of HICAP, MOPP, and HIPP that stands for "Hilar Interneuron with PRojections to the Outer Molecular layer."

Synonym(s)
DG aspiny hilar interneurons with projections to the outer molecular layer
DG spiny hilar interneurons with projections to the outer molecular layer

List of articles
Click here to view the list
Lubke J  (1998) J Neurophysiol
Specialized electrophysiological properties of anatomically identified neurons in the hilar region of the rat fascia dentata.
Lubke J, Frotscher M, Spruston N.
J Neurophysiol, 1998 Mar, 79 (3), Pages: 1518 - 1534
PMID: 9497429
Tags: morphology, membrane biophysics, connectivity, firing patterns, synapse probabilities


Morphology
Soma
DG:H
Axons
DG:SMo
DG:SMi
DG:SG
DG:H
CA3:SR
CA3:SL
CA3:SP
CA3:SO
Dendrites
DG:SMi
DG:SG
DG:H

Representative figure
Specialized electrophysiological properties of anatomically identified neurons in the hilar region of the rat fascia dentata.
Lubke J, Frotscher M, Spruston N
J Neurophysiol, 1998 Mar, 79 (3), pages: 1518 - 1534
PMID: 9497429;


"FIG . 6. Paired morphology and physiology of a [dentate gyrus] spiny hilar interneuron {DG HIPROM}. A: morphology of the biocytin-filled neuron. Axonal projection (red) to the molecular layer is restricted mainly to the outer zone. Note abundant collaterals in the hilus and in area CA3c."


Molecular markers
Positive
None known
Negative
GABAa\alpha 6 (inference)
Mixed expression
None known

Electrophysiological properties
Key: [range] OR representative value±SD (measurements); Number of sources (total measurements): [min , max]

Resting membrane potential (Vrest): -65±6 mV (3); 1 source
Input resistance (Rin): 371±47 MΩ (3); 1 source
Time constant (τm): 35 ms (2); 1 source
Threshold potential (Vthresh): [25.1, 27.3] mV (2); 1 source
Fast afterhyperpolaziring potential amplitude (Fast AHP): 13.1±3 mV (3); 1 source
Action potential amplitude (APampl): 80.8 mV (1); 1 source
Action potential width (APwidth): 0.72±0.08 ms (3); 1 source
Max firing rate (Max F.R.): 69±4 Hz (3); 1 source
Slow afterhyperpolarizing potential amplitude (Slow AHP): 3.1±1 mV (3); 1 source
Sag ratio: 0.82±0.02 (3); 1 source

Notes
N = 3 cells are spiny, N = 4 cells are aspiny. Both spiny and aspiny cells are able to form basket-like bouton arrays on GC somata and somata of other hilar neurons. The youngest rats may be adolescents.

Firing Pattern
Images
Image Missing
Parameters View page
D.ASP. [Evidence] [Firing Pattern]

Izhikevich Model
Parameters Single Compartment Downloads Simulate
subtype: 1 k=2.16;a= 0.001;b= -21.24;d= 28;C= 510;Vr= -65.4;Vt= -45.28;Vpeak= -9.92;Vmin= -49.31; Simulate
Images
Image Missing
ModelDB Model
Model Accession Number PubMed ID

Sources of Input
Known sources
Excitatory or Inhibitory
none known

Potential sources
Excitatory or Inhibitory
DG Granule
DG Adult-Born Immature Granule*
DG Hilar Ectopic Granule
DG Semilunar Granule
DG Mossy
DG Mossy MOLDEN
DG AIPRIM
DG Granulosum-targeting Axo-axonic*
DG Axo-axonic GRALDEN*
DG Basket
DG Basket GRALDEN*
DG Basket CCK+
DG Interneuron Specific COLTAR*
DG COM-MOPP*
DG HICAP
DG Interneuron Specific IMOT*
DG Hilus-Associated Interneuron*
DG Interneuron Specific HIMOLD*
DG Recurrent HIPP*
DG HIPP-CAP*
DG Recurrent HIPP-CAP*
DG Interneuron Specific HIPRO*
DG HIPROM
DG Ivy*
DG MOCAP
DG MOLAX
DG Total Molecular Layer
DG Wide-Arbor Neurogliaform*
CA3c Pyramidal
CA3c Umbrella Pyramidal*
CA3 Spiny Lucidum
CA3 Mossy Fiber-Associated
CA3 Mossy Fiber-Associated ORDEN
CA3 Perforant Path-Associated Projecting*
CA3 Interneuron Specific Quad
CA2 Pyramidal
CA1 Back-Projection
CA1 LMR Projecting
MEC LV Pyramidal

Potential sources known to be avoided
Excitatory or Inhibitory
DG Axo-axonic

Targets of Output
Known targets
Excitatory or Inhibitory
DG Granule

Potential targets
Excitatory or Inhibitory
DG Adult-Born Immature Granule*
DG Hilar Ectopic Granule
DG Semilunar Granule
DG Cajal-Retzius*
DG Local-Projecting Cajal-Retzius*
DG Mossy
DG Mossy MOLDEN
DG AIPRIM
DG Axo-axonic
DG Granulosum-targeting Axo-axonic*
DG Axo-axonic GRALDEN*
DG Basket
DG Basket GRALDEN*
DG Basket CCK+
DG Interneuron Specific COLTAR*
DG COM-MOPP*
DG HICAP
DG Interneuron Specific IMOT*
DG Hilus-Associated Interneuron*
DG Interneuron Specific HIMOLD*
DG HIPP
DG Recurrent HIPP*
DG HIPP-CAP*
DG Recurrent HIPP-CAP*
DG Interneuron Specific HIPRO*
DG HIPROM
DG Ivy*
DG MOCAP
DG MOLAX
DG Molecular Layer*
DG Outer Molecular Layer
DG Total Molecular Layer
DG MOPP
DG Neurogliaform
DG Wide-Arbor Neurogliaform*
CA3 Pyramidal
CA3 Athorny Pyramidal*
CA3c Pyramidal
CA3c Umbrella Pyramidal*
CA3 Giant
CA3 Granule
CA3 Axo-axonic
CA3 Horizontal Axo-axonic
CA3 Basket
CA3 Basket CCK+
CA3 Horizontal Basket CCK+*
CA3 Mossy Fiber-Associated Basket CCK+*
CA3 Bistratified
CA3 Ivy
CA3 Bilayer Ivy*
CA3 LMR-Targeting
CA3 Lucidum*
CA3 Lucidum LAX
CA3 Lucidum ORAX
CA3 Lucidum-Radiatum
CA3 Spiny Lucidum
CA3 Mossy Fiber-Associated
CA3 Mossy Fiber-Associated ORDEN
CA3 O-LM
CA3 Recurrent O-LM*
CA3 Interneuron Specific Oriens
CA3 Perforant Path-Associated*
CA3 Perforant Path-Associated Projecting*
CA3 Interneuron Specific Quad
CA3 QuadD-LM
CA3 Radiatum
CA3 R-LM
CA3 SO-SO
CA3 Trilaminar
CA2 Wide-Arbor Basket
CA1 Neurogliaform Projecting

Potential targets known to be avoided
Excitatory or Inhibitory
none known

Oscillation Phase Locking
Category
Value